A Novel Surgical Technique Involving Bone Fixation Canthoplasty, Middle Lamellar Recession and Mucograft Spacer in Treating Patients with Euryblepharon.

Purpose: Euryblepharon is a rare congenital eyelid malformation characterized by symmetrical horizontal enlargement of the palpebral fissure. The eyelid is shortened vertically compared with the horizontal dimension. The lateral canthus is most commonly affected.

Linear Scleroderma En Coup de Sabre: A Case Series With Eyelid Involvement and Management.

Linear scleroderma en coup de sabre is a rare subtype of localized scleroderma. It is typically characterized by linear sclerosis and atrophy of the skin and underlying dermis affecting the frontoparietal region above the brow. The linear sclerotic lesions rarely extend into the upper eyelid.

Rabbi Moshe Ben Maimon, Better Known as Rambam (1138-1204): Physician, Philosopher, and Adjudicator.

Rabbi Moshe Ben Maimon, known as Maimonides (Hebrew name is Rambam), lived from 1138 to 1204. He was one of the important philosophers, adjudicators, and physicians of the Jews. Rambam's knowledge of Jewish laws and his being a philosopher helped him in his third discipline, medicine.

PREDICTORS OF PSYCHOACTIVE SUBSTANCE USE IN SECONDARY SCHOOL ADOLESCENTS IN GOMBE LOCAL GOVERNMENT AREA, GOMBE STATE - NIGERIA.

Background: Psychoactive substance use among adolescents presents a significant global challenge, contributing notably to morbidity and mortality. Adolescence is a critical developmental phase that is marked by various psycho-social hurdles, yet local data on predictors of substance use remains scarce. This study aims to illuminate these issues within Gombe State, providing essential data for evidence-based interventions.

Outbreak of Alternaria Black Spot of Pomegranate ( L.) in Italy as a Consequence of Unusual Climatic Conditions.

Alternaria black spot of pomegranate () was reported for the first time in Italy. In spring 2023, an outbreak of this disease was noticed in commercial pomegranate 'Wonderful' orchards of the municipality of Misterbianco (Sicily), following an unusually rainy period. A total of 30 randomly selected isolates recovered from typical necrotic spots of leaves and fruits were characterized.

Capturing the cervical spine shape: Angular measurements versus geometric morphometric methods.

The cervical spine manifests a wide shape variation. However, the traditional methods to evaluate the cervical spine curve were never tested against its actual shape. The study's main aim was to determine whether the shape classification of the cervical spine, based on traditional angular measurements, coincides with each other and with the shape captured by the 2D landmark-based geometric morphometric method.

The Posthyaluronidase Syndrome: Dosing Strategies for Hyaluronidase in the Dissolving of Facial Filler and Independent Predictors of Poor Outcomes.

Background: Hyaluronic acid dermal fillers are used extensively in periocular aesthetic medicine, and the incidence of filler-related complications is increasing. This study aimed to investigate the optimal dosing strategy for hyaluronidase and to identify predictors of poor outcomes.

Methods: We performed a retrospective review of 157 orbits of 90 patients treated with hyaluronidase over a 4-year period.

Autotrophic growth of is achieved by a small number of genetic changes.

Synthetic autotrophy is a promising avenue to sustainable bioproduction from CO. Here, we use iterative laboratory evolution to generate several distinct autotrophic strains. Utilising this genetic diversity, we identify that just three mutations are sufficient for to grow autotrophically, when introduced alongside non-native energy (formate dehydrogenase) and carbon-fixing (RuBisCO, phosphoribulokinase, carbonic anhydrase) modules.

Safety and Efficacy of Mucograft Porcine Collagen Bioengineered Acellular Dermal Matrix as a Spacer Graft in Lower Eyelid Elevation Surgery.

Background: Recent regulatory changes have limited the access to a widely used commercially available bioengineered acellular dermal matrix (BADM) product as a spacer graft in the surgical correction of lower eyelid retraction. We report our off-label usage of Mucograft, a porcine BADM, as an alternative BADM.

Methods: A retrospective review was conducted of patients undergoing bilateral lower lid surgery with Mucograft (12 eyes) at a single institution.

Quantitative Assessment of Periocular Autologous Fat Transfer Survival Using 3D Stereophotogrammetric Imaging.

Purpose: To assess periocular autologous fat transfer (AFT) survival by assessment of volume change with sequential 3D VECTRA imaging.

Objective: Little is known about the patterns of graft survival of AFT in the periorbital region, especially in cases involving prior radiotherapy or trauma. The aim of this pilot study was to characterize fat survival following AFT in patients with a broad range of clinical indications, with and without a history of prior radiotherapy, for both periocular and orbital AFT, and in a subgroup of patients with an anophthalmic socket.

A guide to the use of bioassays in exploration of natural resources.

Bioassays are the main tool to decipher bioactivities from natural resources thus their selection and quality are critical for optimal bioprospecting. They are used both in the early stages of compounds isolation/purification/identification, and in later stages to evaluate their safety and efficacy. In this review, we provide a comprehensive overview of the most common bioassays used in the discovery and development of new bioactive compounds with a focus on marine bioresources.

Physical and psychosocial work demands associated with pain and disability among skilled male Arab waiters.

Background: Physical and psychosocial demands (e.g., serving, cleaning, fulfilling orders) can lead to work-related musculoskeletal pain (WRMSP).

METABOLIC SYNDROME AND ASSOCIATED RISK FACTORS AMONG SECONDARY SCHOOL ADOLESCENTS IN NORTHEAST NIGERIA.

Introduction: Metabolic syndrome (MetS) is a cluster of risk factors that may predispose to cardiovascular diseases and type 2 diabetes mellitus. These risk factors include hypertension, central obesity, hyperglycaemia, hypertriglyceridemia and low high-density lipoprotein cholesterol (HDL-C). The presence of at least three of these risks factors defines MetS.

, a Bacterial Endophyte of the Marine Macroalga , Emits 8-Nonenoic Acid Which Inhibits the Aquaculture Pathogen .

Secondary metabolites-organic compounds that are often bioactive-produced by endophytes, among others, provide a selective advantage by increasing the organism's survivability. Secondary metabolites mediate the symbiotic relationship between endophytes and their host, potentially providing the host with tolerance to, and protection against biotic and abiotic stressors. Secondary metabolites can be secreted as a dissolved substance or emitted as a volatile.

Twenty Intracranial Skull Base Variations in the Same Specimen.

Anatomists and clinicians often encounter single bony anatomical variations in dry skulls and on imaging. However, a constellation of 20 such variants some that, to our knowledge, have not been previously described is noteworthy. Here, we describe an adult skull with multiple bony variations, and these are detailed and discussed.

Tear Trough Filler Using the Three-point Tangent Technique: Lessons from 1452 Tear Trough Applications.

Unlabelled: This study describes a novel three-point tangent technique for tear trough filler and the results from the largest series to date.

Methods: A retrospective case review was performed for all patients treated between 2016 and 2020. Patient demographics, filler details and complications were recorded.

"Star like" disease of persimmon () fruit caused by in Israel.

During May 2016, a corky textured, "star like" symptom, located at the apex on the far side of the fruit was observed on young persimmon fruitlets (Fig. 1), on several persimmon varieties in plantations located along the Mediterranean Sea coast. The lesions caused cosmetic damage, which disqualified the fruit from marketing and can affect as much as 50% of the fruit in the orchard.

Morphologic aspects of the cervical (C3-C7) annular epiphysis: a skeletal study.

Background Context: The annular epiphysis (AE) is a peripheral ring of cortical bone that forms a secondary ossification center in the superior and inferior surfaces of vertebral bodies (VBs). The AE is the last ossification site in the skeleton, typically forming at about the 25th year of life. The AE functions jointly with vertebral endplates to anchor the intervertebral discs to the VBs.

The Whitnall Barrier: A Technique for the Management of Lacrimal Gland Prolapse.

Background: The Whitnall barrier procedure, a modified Beer and Kompatscher surgical technique to reposition the lacrimal gland, is presented alongside a case series of patients demonstrating excellent aesthetic and functional outcomes.

Methods: The Whitnall barrier procedure is illustrated procedurally and accompanied by a case series of 20 consecutive patients treated in a single institution by a single surgical team between December of 2016 and February of 2020. Lid contour and function were assessed postoperatively, as was patient satisfaction.

Endophytic Penicillium species secretes mycophenolic acid that inhibits the growth of phytopathogenic fungi.

The worldwide demand for reduced and restricted use of pesticides in agriculture due to serious environmental effects, health risks and the development of pathogen resistance calls for the discovery of new bioactive compounds. In the medical field, antibiotic-resistant microorganisms have become a major threat to man, increasing mortality. Endophytes are endosymbiotic microorganisms that inhabit plant tissues without causing any visible damage to their host.