Publications by authors named "Ezinwanne N Ezeibe"
Article Synopsis
- * Preventive measures, such as social distancing and mask-wearing, have helped slow the virus's spread; however, the persistent nature of the virus and its variants makes complete eradication difficult.
- * The development of effective vaccines relies heavily on nanotechnology, which enhances vaccine delivery and efficacy; currently, four vaccines are approved for use, with more in progress.
Background: Artemether and lumefantrine display low aqueous solubility leading to poor release profile; hence the need for the use of lipid-based systems to improve their oral bioavailability so as to improve their therapeutic efficacy.
Aim And Objective: The objective of this work was to utilize potentials of nanostructured lipid carriers (NLCs) for improvement of the oral bioavailability of artemether and lumefantrine combination and to evaluate its efficacy in the treatment of malaria. This study reports a method of formulation, characterization and evaluation of the therapeutic efficacies of caprol-based NLC delivery systems with artemether and lumefantrine.
While studies have explored how health sector corruption, weak healthcare system, large-scale immune compromised population, misinformation and prevalence of highly congested slums contribute to the spread of COVID-19 in Nigeria, they have glossed over the impact of political distrust on the spread of the virus. This study explores the impact of political distrust on the spread of COVID-19 pandemic in Nigeria. The study utilised qualitative dominant mixed methods approach comprising telephone interviews and a survey of 120 educated Nigerians purposively selected from four COVID-19 most affected states including Lagos, Oyo, Kano and Rivers as well as the Federal Capital Territory, Abuja.
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