Selective arm-usage of pre-miR-1307 dysregulates angiogenesis and affects breast cancer aggressiveness.

Background: Breast cancer is the leading cause of cancer-related mortality in women. Deregulation of miRNAs is frequently observed in breast cancer and affects tumor biology. A pre-miRNA, such as pre-miR-1307, gives rise to several mature miRNA molecules with distinct functions.

Evaluation of Quality of Life and Psychosocial Status in Children with Inflammatory Bowel Disease.

Objectives: Inflammatory bowel disease (IBD) in children is a chronic condition that affects the psychosocial status and physical activities of children and their parents. This study aimed to investigate the impact of IBD on the quality of life of adolescents and their families and the variability of behavioral and emotional adjustment issues compared to a healthy control group.

Methods: This study was designed as a prospective controlled study.

Depression and parental distress among caregivers of autistic children: a serial mediator analysis in caregivers of autistic children.

Background: This study aimed to investigate the relationship between the severity of autism, emotional and behavioral problems of autistic children, internalized stigma, depressive symptoms, and primary caregiver parental stress. Specifically, we explored the mediating role of internal stigmatization and total difficulties of individuals with autism on parenting stress and depressive symptoms of the primary caregiver.

Method: Mothers of 93 children with autism were included in the study.

Reliability and validity of the brief version of the difficulties in emotion regulation scale in a sample of Turkish adolescents.

Background: Difficulty in regulating emotions increases during adolescence and can be associated with psychopathology. It is thus crucial to develop tools to identify adolescents at risk of having emotional difficulties. This study aimed to investigate the reliability and validity of a brief questionnaire in a sample of Turkish adolescents.