Bioactivities and HPLC analysis of secondary metabolites of a morphologically identified endophytic fungus isolated from .

Natural products from Nigerian plants are significant in the search for drug compounds, as they contribute new compounds with biological properties to the fight against resistant pathogens, hence the study. Fresh leaves of were prepared for fungal isolation, identification, fermentation, and secondary metabolites extraction. The extract, subjected to HPLC analysis revealed the presence of two bioactive compounds: p-Hydroxylbenzoic acid, and Protocatechuic acid.

Cytotoxic effect and antioxidant activity of pterocarpans from root.

Chemical analysis of the methanol extract of the root bark of led to the isolation of homopterocarpin (), secundiflorol I (), and maackain (). The structures of these compounds were elucidated based on their MS and NMR spectra. The crude methanol root extract was screened for its cytotoxic activity on mouse lymphoma cell line (L5178Y), and the isolated compounds were tested for their antioxidant activity using a 2, 2-diphenylhydrazyl (DPPH) radical scavenging model.

Larvicidal activity of the leaf extracts of Spondias mombin Linn. (Anacardiaceae) from various solvents against malarial, dengue and filarial vector mosquitoes (Diptera: Culicidae).

Background & Objectives: Aedes aegypti, Anopheles gambiae and Culex quinquefasciatus are vector mosquitoes of dengue, malaria, and filariasis, respectively. Since no vaccine is available to treat these diseases, the control of the main mosquito vectors is essential. As conventional insecticides have limited success, plants may be alternative larvicidal agents, since they contain a rich source of bioactive chemicals.