Publications by authors named "Ezarul Faradianna Lokman"
Article Synopsis
- Children often catch infections from school activities and poor hygiene, which negatively impacts attendance and health.
- A systematic review analyzed studies on school-based hygiene interventions, finding a mix of results and low-to-moderate certainty in evidence due to methodological flaws.
- Interventions showed promise in improving hand-body hygiene knowledge, practices, and reducing absenteeism but had mixed effects on oral hygiene, with some indications of both improvement and decline in dental health outcomes.
The beneficial effects of resistant starch (RS) consumption on health in terms of reducing postprandial hyperglycaemia are evident. However, the potential of local Sarawak sago RS in regulating glucose has not been extensively studied. This study aims to identify glucose-lowering effects of Sarawak sago RS, namely native (RS2) and chemically modified (RS4).
View Article and Find Full Text PDFSimple lifestyle changes can prevent or delay the onset of type 2 diabetes mellitus (T2DM). In addition to maintaining a physically active way of life, the diet has become one of the bases in managing TD2M. Due to many studies linking the ability of resistant starch (RS) to a substantial role in enhancing the nutritional quality of food and disease prevention, the challenge of incorporating RS into the diet and increasing its intake remains.
View Article and Find Full Text PDFBackground: Maternal hyperglycemia is associated with increased risk of adverse outcomes for both mother and offspring. Insulin is the standard treatment of hyperglycemia with the aim to reduce risks of complications, however, due to several restrictions, the search for more effective drugs from traditional medicinal plants continues.
Methods: The antidiabetic effects of ( in non-pregnant and pregnant streptozotocin-induced Sprague Dawley rats were identified.
() is the most well-known starchy tuber in Malaysia and called 'ubi gadong'. Despite concerns over toxicity effects, the tuber is known to possess therapeutic values due to the presence of bioactive compounds such as saponins. This study was performed to identify the changes in gene expression profiles associated with hepatoxicity in pregnant rat treated with using RT² Profiler PCR Array.
View Article and Find Full Text PDFAims. To evaluate the antidiabetic effects of Gynostemma pentaphyllum (GP) in Goto-Kakizaki (GK) rat, an animal model of type 2 diabetes, and to investigate the mechanisms of insulin release. Methods.
View Article and Find Full Text PDFObjective: Hypoxia plays a major pathogenic role in diabetic nephropathy (DN). We have investigated in this study the effect of hypoxia-inducible factor 1 α subunit (HIF1A) genetic polymorphisms on the development of DN.
Research Design And Methods: In 1,165 American type 1 diabetic patients with and without DN selected from the Genetics of Kidneys in Diabetes (GoKinD) study, the HIF1A genetic polymorphisms were genotyped with TaqMan allelic discrimination.