Evaluation of Oxidative Stress and Cellular Immunity in Grades III-IV Knee Osteoarthritis.

Objectives: In this study, the Kellgren and Lawrence system was used as the most common radiographic grading system for diagnosis of osteoarthritis in patients defined as Grade III and IV. It is aimed to reveal oxidative stress and cellular immunity status. In this context, the aim is to discuss possible risk parameters regarding disease process and treatment effectiveness.

The Relationship Between Substance Abuse Proclivity and Spiritual Well-Being Levels of University Students in Türkiye.

Focusing on young adults constituting the most vulnerable and risky group regarding substance abuse, the present study was carried out in order to examine the relationship between the spiritual well-being levels of university students and their substance abuse proclivity. Having a descriptive and cross sectional design, this study was completed with 250 students studying at a Vocational High School of a university in Türkiye during the academic year 2021-2022. The data collection process was carried out by using the "Personal Information Form," the "Spiritual Well-Being Scale (SWBS)," and the "Substance Use Tendency Scale (SAPS).

Could MOTS-C Levels in Children with Type 1 Diabetes Mellitus Be an İndicator for Early Diabetic Kidney Disease?

Objective: The aim of our study was to compare serum MOTS-c levels in children with Type 1 diabetes mellitus (T1DM) to those of healthy children. We also aimed to examine whether serum MOTS-c levels could be used as an early indicator of DKD by correlating with changes in GFR and microalbuminuria.

Methods: We recruited 82 patients who were being treated for insulin-dependent diabetes at the outpatient pediatric endocrinology clinic.

Contrast induced nephropathy in women with infertility undergoing hysterosalpingography.

Background: Contrast-induced nephropathy (CIN) defined as an acute kidney injury following the administration of iodinated contrast medium (CM). Hysterosalpingography (HSG) is a radiologic procedure used to investigate the shape and structure of the uterine cavity and the patency of the fallopian tubes in the evaluation of infertility. To date, there have been no reports evaluating the development of CIN after HSG procedure.

Precision oncology: Using cancer genomics for targeted therapy advancements.

Cancer genomics plays a crucial role in oncology by enhancing our understanding of how genes drive cancer and facilitating the development of improved treatments. This field meticulously examines various cancers' genetic makeup through various methodologies, leading to groundbreaking discoveries. Innovative tools such as rapid gene sequencing, single-cell studies, spatial gene mapping, epigenetic analysis, liquid biopsies, and computational modeling have significantly progressed the field.

Effect of aromatherapy on pruritus in people receiving hemodialysis treatment: Systematic review.

Background: Lack of a complete understanding of the pathophysiology of pruritus directs patients to different treatments. There is little data on the effect of aromatherapy on itching in patients receiving hemodialysis treatment. However, the effect of aromatherapy on pruritus in patients receiving hemodialysis treatment remains unclear.

Soluble ST2 as a Biomarker for Predicting Right Ventricular Dysfunction in Acute Pulmonary Embolism.

Suppression of Tumorigenicity 2 (ST2), a member of the interleukin-1 (IL-1) superfamily, is recognized as an important biomarker in inflammatory responses and cardiovascular diseases. Elevated serum levels of sST2 have prognostic value, particularly in cases of cardiac stress such as heart failure and acute pulmonary embolism (APE). We aimed to assess ST2 levels as a potential biomarker for right heart dysfunction in APE patients, particularly in the context of its limited predictive value for mortality and risk stratification.

The Impact of the SMOTE Method on Machine Learning and Ensemble Learning Performance Results in Addressing Class Imbalance in Data Used for Predicting Total Testosterone Deficiency in Type 2 Diabetes Patients.

Background And Objective: Diabetes Mellitus is a long-term, multifaceted metabolic condition that necessitates ongoing medical management. Hypogonadism is a syndrome that is a clinical and/or biochemical indicator of testosterone deficiency. Cross-sectional studies have reported that 20-80.

Effects of Botulinum Toxin Type A Treatment on Clinical and Biophysical Parameters in Patients With Erythematotelangiectatic Rosacea: A Prospective, Randomized, Controlled, Double-Blind Study.

Background: Erythematotelangiectatic rosacea (ETR) lacks a gold-standard treatment. Recent studies show that intradermal Botulinum Toxin-A (BoNT-A) is effective for erythema, though objective data are limited.

Objective: This study aims to evaluate the efficacy and tolerability of intradermal BoNT-A in patients with ETR.

Postoperative Analgesic Efficacy of Clavipectoral Plane Block and Serratus Posterior Superior Intercostal Plane Block Combination in Clavicle Surgeries: A Report of 10 Cases.

This case series included 10 patients who underwent clavicular fracture surgery under general anesthesia. A novel analgesic approach combining 2 distinct nerve block techniques-serratus posterior superior intercostal plane block (SPSIPB) and clavipectoral plane block (CPPB)-was used for postoperative pain management. SPSIPB provided sensory blockade for the innervation of the clavicular skin, whereas CPPB targeted the clavipectoral fascia.

EFFICACY AND SAFETY OF GUIDELESS CATHETER PLACEMENT IN REVISION EXTERNAL VENTRICULAR DRAINAGE AND VENTRICULAR SHUNT SURGERY.

Aim: This study aims to evaluate the efficacy and safety of the guideless catheter placement technique in revision surgeries for external ventricular drainage (EVD) and ventricular shunt systems to improve treatment outcomes for hydrocephalus.

Material And Methods: We retrospectively analyzed 111 patients who underwent revision surgeries for EVD or ventricular shunt systems at the *BLINDED FOR REVIEW* from January 2020 to January 2023. Patients' demographic (age, sex) and clinical (cause of hydrocephalus, type of surgery, and postoperative complication rates, specifically for bleeding and catheter malposition) data were extracted from the patient files.

Psychological and Pain Factors in Microsurgical Testicular Sperm Extraction (Micro-TESE) for Non-Obstructive Azoospermia: A Comparative Study of Successful and Unsuccessful Cases.

Purpose: This study aimed to assess postoperative pain, depression, and anxiety levels in infertile men who underwent microsurgical testicular sperm extraction (micro-TESE) for non-obstructive azoospermia (NOA) and compare results between patients with successful and unsuccessful sperm retrieval.

Material And Methods: A total of 105 NOA patients participated, completing preoperative Beck Depression Inventory (BDI) and Situational and Transient Anxiety Inventory (SAI and TAI) questionnaires. Postoperatively, Visual Analog Scale (VAS) scores were recorded.

Comparison of athletic performance of Turkish ice hockey players with ACE I/D (rs1799752), ACTN3 (rs1815739), PPARA (rs4253778) and HIF1A (rs11549465) polymorphisms.

Our study is aimed at examining the Ice Hockey National Team players with regard to ACE I/D (rs1799752), ACTN3 (rs1815739), PPARA (rs4253778) and HIF1A (rs11549465) polymorphisms and physical tests. This study was participated by 21 players from ice hockey national team. While ACE I/D (rs1799752) polymorphism was obtained using conventional polymerase chain reaction method (PCR), ACTN3 (rs1815739), PPARA (rs4253778) and HIF1A (rs11549465) polymorphisms were produced by real time polymerase chain reaction method (qPCR).

Risk Factor Analysis Including Inflammatory Markers for ICU Admission and Survival After Pneumonectomy.

To assess the impact of preoperative inflammatory parameters on the necessity for intensive care unit (ICU) admission and survival after pneumonectomy. We enrolled 207 adult patients who underwent pneumonectomy between December 2016 and January 2022. We collected data from patients' electronic medical records.

Assessment of Internet and Social Media Addiction Levels in Adolescents Aged 12-18 Years by Nurses: A Multicenter Cross-Sectional Study.

Objective: This was a cross-sectional and descriptive study to determine the social media and Internet addiction levels of adolescents.

Design And Methods: The data were collected between September and December 2023. A sociodemographic data collection form, The Social Media Addiction Scale for Adolescents, and The Internet Addiction Scale for Adolescents were used to collect data.