Vestibular Rehabilitation Using Dynamic Posturography: Objective and Patient-Reported Outcomes from a Randomized Trial.

Objective: Balance deficits are common and debilitating. Standard treatments have limitations in addressing symptoms and restoring dynamic balance function. This study compares a rehabilitative computerized dynamic posturography (CDP) protocol, computerized vestibular retraining therapy (CVRT), with a home exercise program (HEP) for patients with objectively confirmed unilateral vestibular deficits (UVDs).

Dynamic posturography after computerized vestibular retraining for stable unilateral vestibular deficits.

Background: Balance deficits increase the risk of falls and compromise quality of life. Current treatment modalities do not resolve symptoms for many patients.

Aims/objectives: To measure changes in objective posturography after a computerized vestibular retraining therapy protocol.

Durable improvement in participant-reported measures of disability and objective posturography after computerized vestibular retraining.

Background: Unilateral vestibular deficits are associated with postural instability and loss of quality of life. Common treatments frequently fail to achieve satisfactory outcomes.

Objective: To assess the durability of changes in participant-reported disability and objective posturography after computerized vestibular retraining.

Fall Risk and Functional Stability Before vs After Computerized Vestibular Retraining Among Adults With Unilateral Vestibular Deficits.

This cohort study compares dynamic postural stability and risk of falls before and after computerized vestibular training among adults with unilateral vestibular deficits.

Patient-Reported Disability After Computerized Posturographic Vestibular Retraining for Stable Unilateral Vestibular Deficit.

Importance: Individuals with persistent unilateral vestibular deficits experience loss of quality of life and increased risk of falling, and they have few well-supported options for effective treatment.

Objectives: To evaluate whether vestibular retraining using computerized dynamic posturography is associated with reduced participant-reported disability for patients with an objectively assessed unilateral peripheral vestibular deficit and to assess the feasibility of conducting a randomized clinical trial of vestibular retraining using computerized dynamic posturography.

Design, Setting, And Participants: This single-group cohort study was conducted from April 29 to July 23, 2021, in a tertiary neurotology clinic among 13 individuals with a stable unilateral vestibular deficit present for more than 6 months, confirmed with videonystagmography and vestibular evoked myogenic potential testing.

Normal values for cervical and ocular vestibular-evoked myogenic potentials using EMG scaling: effect of body position and electrode montage.

Background: The clinical utility of cervical and ocular vestibular-evoked myogenic potential (cVEMP and oVEMP) is limited by variability of testing protocols and a dearth of normative data using contemporary methods for amplitude scaling.

Aims/objectives: To investigate the effect of body position and electrode montage on VEMP responses and to establish normative values.

Material And Methods: This is a repeated measures study of 44 healthy young adult subjects (22 men and 22 women).

Medial canal fibrosis: surgical technique, results, and a proposed grading system.

Objective: To report the hearing and surgical results in patients with medial canal fibrosis. To describe the surgical technique for removal of medial canal fibrosis and to propose a classification for grading postoperative surgical outcome and to correlate this with hearing results.

Setting: Tertiary university referral center.

Evaluation of the high-resolution speech coding strategy for the Clarion CII cochlear implant system.

Four postlinguistically deafened adults were implanted with the Clarion CII cochlear implant with the HiFocus II electrode in an evaluation of performance with a new speech coding strategy (high resolution) compared with current speech coding strategies (multiple pulsatile sampler, continuous interleaved sampling, and simultaneous analog stimulation). These strategies were implemented in the Platinum speech processor from Advanced Bionics Corporation (Sylmar, CA). Postoperatively, subjects were fitted with the traditional coding strategies and over the first month were allowed to determine their strategy of choice.

Cochlear delivery of fibroblast growth factor 1 and its effects on apoptosis and cell cycling in noise-exposed guinea pig ears.

Objectives: Acidic fibroblast growth factor 1 (FGF-1) is a mitogen and antiapoptotic factor synthesized by cochlear neurons and transported to the organ of Corti. The objectives of this investigation were threefold: (1) to develop an animal model to study the cochlear effects of intratympanic delivery of FGF-1; (2) to determine the distribution, in the mature mammalian cochlea, of FGF-1 and the receptor, FGFR3, to which it binds with high affinity; and (3) to examine the effect of exogenous FGF-1 on cochlear apoptotic and cell-cycling markers in noise and non-noise-exposed guinea pigs ears.

Methods: Fifteen adult Hartley guinea pigs were divided into three groups.