Central nervous system (CNS) involvement is a rare and aggressive complication of multiple myeloma (MM). We identified 54/4352 MM patients (1.2%), who developed CNS-MM between 2000 and 2022.
Researchers studied how effective new treatments called VRd and DBQ are for patients with a type of blood cancer called primary plasma cell leukemia (pPCL) compared to older treatments.
They looked at 110 patients and found that those treated with the new treatments had better results, with nearly 83% of them responding well to the treatment.
Overall, patients using VRd/DBQ lived longer and had fewer complications than those on older treatments, making it the best option for treating pPCL right now.