Endemic medicinal plants of Ethiopia: Ethnomedicinal uses, biological activities and chemical constituents.

Ethnopharmacological Relevance: Around 80% of Ethiopians rely on traditional medicinal plants to treat a variety of ailments, and the country is home to a number of endemic plants, making it part of East Africa's hotspot of biodiversity. Despite widespread acceptance of endemic medicinal plants among the local community, comprehensive documentation of their therapeutic uses and phytochemistry is lacking. This review thus provides the first comprehensive appraisal of traditional use, pharmacological properties and phytochemistry of Ethiopian endemic medicinal plants.

Ethiopian Medicinal Plants Traditionally Used for the Treatment of Cancer, Part 2: A Review on Cytotoxic, Antiproliferative, and Antitumor Phytochemicals, and Future Perspective.

This review provides an overview on the active phytochemical constituents of medicinal plants that are traditionally used to manage cancer in Ethiopia. A total of 119 articles published between 1968 and 2020 have been reviewed, using scientific search engines such as ScienceDirect, PubMed, and Google Scholar. Twenty-seven medicinal plant species that belong to eighteen families are documented along with their botanical sources, potential active constituents, and in vitro and in vivo activities against various cancer cells.