Publications by authors named "Exeli A"

Article Synopsis
  • A case study highlights the use of a large myomatous uterus as a natural spacer during radiation therapy for a female patient with locally advanced anal carcinoma, helping to protect the bowel from excess radiation exposure.
  • The patient initially presented with anal pain, and subsequent examinations confirmed a diagnosis of squamous cell carcinoma, with imaging revealing a large uterus containing multiple leiomyomas.
  • The presence of these leiomyomas minimized the radiation dose to the small intestine, leading to virtually no acute gastrointestinal toxicity during the patient's chemoradiation treatment.
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Background: We retrospectively investigate feasibility and safety of whole brain radiotherapy (WBRT) including a simultaneous-integrated boost technique (WBRT-SIB) in a cohort of patients with a very poor prognosis suffering from multiple and/or large brain metastases, unfavorable primary histology, poor performance status and/or symptomatic BMs.

Materials And Methods: Thirty-five patients with high brain tumor burden, extracranial metastases and low life-expectancy were treated with WBRT-SIB mostly with 35-42 Gy/14 fractions. All metastases were boosted in patients with up to 12 BMs.

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Background: To date, patients with glioblastoma still have a bad median overall survival rate despite radiation dose-escalation and combined modality treatment. Neurocognitive decline is a crucial adverse event which may be linked to high doses to the cortex. In a planning study, we investigated the impact of dose constraints to the cerebral cortex and its relation to the organs at risk for glioblastoma patients.

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Background: To report acute and late toxicity with long-term follow-up, and to describe our experiences with pulmonary dose constraints.

Methods: Between 2002 and 2009, 150 patients with 155 histologically/cytologically proven non-small cell lung cancer (NSCLC; tumor stages II, IIIA, IIIB in 6, 55 and 39%, respectively) received the following median doses: primary tumors 79.2 Gy (range 72.

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Background: One of the primary dose-limiting toxicities during thoracic irradiation is acute esophagitis (AE). The aim of this study is to investigate dosimetric and clinical predictors for AE grade ≥ 2 in patients treated with accelerated radiotherapy for locally advanced non-small cell lung cancer (NSCLC).

Patients And Methods: 66 NSCLC patients were included in the present analysis: 4 stage II, 44 stage IIIA and 18 stage IIIB.

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