Macrophage Migration Inhibitory Factor is not Associated with Sarcoidosis Susceptibility or Severity in Whites or Blacks.

Background: Macrophage migration inhibitory factor (MIF) is an inflammatory cytokine, and increased expression has been associated with the development and severity of multiple granulomatous, autoimmune diseases. However, association studies have been discordant in sarcoidosis.

Objective: To evaluate associations between macrophage migration inhibitory factor () promoter polymorphisms and sarcoidosis susceptibility and severity.