Influence of diet on the risk of developing endometriosis.

Endometriosis is a hormone-dependent chronic inflammatory disease characterized by the presence of endometrium beyond the uterine cavity. The disease affects 5-15% of women of child-bearing age, 30-50% of whom suffer from infertility. Understanding the role of dietary factors in the development of endometriosis is critical to development of effective dietary instructions for prevention.

Expression Profiles of Toll-Like Receptors in the Differentiation of an Infection with Borrelia burgdorferi Sensu Lato Spirochetes.

The similarity of Lyme borreliosis to other diseases and its complex pathogenesis present diagnostic and therapeutic difficulties. The changes that occur at the cellular and molecular levels after a Borrelia sp. infection still remain poorly understood.

Usefulness of magnetic resonance imaging as a prognostic variable in myelodysplastic syndromes.

Background: Myelodysplastic syndromes are clonal disorders of stem cells, characterized by heterogeneous clinical presentation. Hematopoiesis is ineffective, characterized by abnormal differentiation, maturation and survival of hematopoietic cells.

Material And Methods: The examinations were conducted in the Hematology Ward and the Internal Medicine Ward of the Specialist Hospital No.

Usefulness of spinal magnetic resonance imaging in patients with myelodysplastic syndromes.

Background: Myelodysplastic syndrome is a rare, chronic hematological disease characterized by heterogeneous clinical presentations. Subtypes of myelodysplastic syndrome are characterized by different survival times and ability to transform into acute myeloid leukemia.

Objectives: The objective of the study included the assessment of the relationship between the images obtained by magnetic resonance scans of lumbar spine and the clinical symptoms of the disease in patients diagnosed with myelodysplastic syndrome, as well as the assessment of the correlation of the images with the phase of transformation into acute myeloid leukemia.

[The role of complement factor H in the pathogenesis of Borrelia infection].

Complement factor H (CFH) is one of the most important negative regulators of the alternative pathway of the complement system. It is a glycoprotein belonging to the protein H family, which is synthesized mainly in the liver and is composed into a globular protein consisting of 60 amino acid domains in the serum. It shows specificity for C3b molecule of the complement system present in the serum or bound to the cell surface.

The role of human endogenous retroviruses in the pathogenesis of autoimmune diseases.

This paper presents a new, recently formulated theory, which concerns the etiopathological process of autoimmune diseases. This theory takes into account the existence in the human genome, since approximately 40 million years, of so-called human endogenous retroviruses (HERVs), which are transmitted to descendants "vertically" by the germ cells. It was recently established that these generally silent sequences perform some physiological roles, but occasionally become active and influence the development of some chronic diseases like diabetes, some neoplasms, chronic diseases of the nervous system (eg, sclerosis multiplex), schizophrenia and autoimmune diseases.

[Problems of diagnosis and therapy of primary hyperparathyroidism--case report].

Primary hyperparathyroidism is systemic, polymorphic disease. Authors present a case of woman suffered from primary hyperparathyroidism misdiagnosed as disseminated neoplastic disease. There was shown a clinical picture complex, difficulties in diagnostic process, treatment and factors provided mistakes in therapy.

[Abandoning of breast cancer radical treatment--own observations].

Breast cancer is currently one of the most frequent cancers women in Poland suffer from. Incidence increases after 35 years of age and this rate remains high until the old age. Since the 1980s breast cancer has been the most frequent reason for deaths of women between 40 and 59 years of age.

[Sigmoido-vesical fistula as a cause of recurrent urinary tract infections].

The authors describe a case of sigmoido-vesical fistula in 64 years old woman. The fistula probably developed as a result of complications of sigmoidal diverticulitis. The main clinical manifestation were symptoms of recurrent urinary tract infections and pneumaturia.

[Effect of palliative chemotherapy with topoisomerase inhibitor on the quality of life and survival of patients with advanced colorectal carcinoma].

Among several topoisomerase I inhibitors topotecan is worth taking into account because of its little toxicity, good tolerance and quick excretion. The study compared functioning of bone marrow, liver and kidneys during and after the treatment, as well as survival period and quality of life of patients treated with topotecan and patients who underwent symptomatic treatment. 35 patients aged 43-71 of both sexes, with advanced stage of large intestine cancer (IV grade in TNM scale) were included in the study.

[Evaluation of the usefulness and effectiveness of anxiolytic therapies in neoplastic diseases].

Unlabelled: Anxiety accompanies patients at all stages of severe somatic diseases as well in the course of diagnostic procedures. It affects significantly quality of life of these patients and their relations with their physicians. It may also induce or exacerbate wide range of somatic complaints.