Publications by authors named "Ewa Warchol-Celinska"

Introduction: Although renal stenting is the standard revascularization method for atherosclerotic renal artery stenosis (RAS) (FMD-RAS), stenting in fibromuscular dysplasia (FMD) RAS is usually limited to periprocedural complications of angioplasty and primary arterial dissection. The main aim of the study was to retrospectively analyze the immediate and long-term results of renal stenting versus angioplasty in patients with FMD.

Methods: Of 343 patients in the ARCADIA-POL registry, 58 patients underwent percutaneous treatment due to FMD-RAS (in 70 arteries).

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Background: The growing number of adult patients after the Fontan operation requires regular surveillance tests in specialized centers.

Aims: Our study aimed to evaluate the current practice of care for Fontan patients in Poland using a multicenter survey.

Methods: Eight centers were included in the study including 5 adult congenital heart disease (ACHD) and 3 pediatric centers for adolescents.

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Objective: The aim of the study was to investigate a new possible background of increased risk of cardiovascular events in two forms of endocrine hypertension: in primary aldosteronism (PA) and pheochromocytoma/paraganglioma (PPGL) in comparison to essential hypertension (EHT).

Context: Prothrombotic properties of the fibrin clot structure, impaired fibrinolysis and enhanced thrombin generation have been reported to be associated with increased cardiovascular risk.

Design: Patients with PA and PPGL were evaluated at baseline and re-evaluated 3 months after causative treatment.

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Article Synopsis
  • Fibromuscular dysplasia (FMD) is a condition that primarily affects women and can lead to serious health issues like hypertension and strokes; recent research involved a large study comparing FMD cases with controls.
  • The study identified a genetic basis for FMD, discovering several significant gene loci linked to the disease that are involved in arterial cell functions and vascular contraction.
  • Additionally, there is a notable genetic connection between FMD and other common cardiovascular conditions, suggesting shared underlying mechanisms across these diseases.
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Fibromuscular dysplasia (FMD) is a non-atherosclerotic vascular disease that may involve medium-sized muscular arteries throughout the body. The majority of FMD patients are women. Although a variety of genetic, mechanical, and hormonal factors play a role in the pathogenesis of FMD, overall, its cause remains poorly understood.

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In December 2018, an article summarizing available results of randomized studies on renal denervation (RDN), entitled "Renal denervation: can we press the ON button again?" was published in the . Since then, several positive reports, including SPYRAL HTN OFF-MED Pivotal trial have been presented. In the current review the authors discuss the latest data on RDN in arterial hypertension treatment and try to answer the burning question: can we press the ON button again in 2020? The results of recently published studies potentially justify new recommendations for the use of RDN in clinical practice in appropriately selected patients in the new hypertension guidelines.

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Objectives: This study sought to evaluate left ventricular (LV) structure and function in pheochromocytoma and paraganglioma (PPGL) patients before and after curative surgery.

Background: Data on catecholamine-induced effects on LV structure and function in patients with PPGL are limited and conflicting.

Methods: The study evaluated 81 consecutive patients with a PPGL, among whom 66 were evaluated 12 months after tumor removal.

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Current literature suggests a higher risk of pregnancy-related complications in patients with renal fibromuscular dysplasia (FMD). The aim of our study was to assess the nature and prevalence of pregnancy-related complications in patients subsequently diagnosed with FMD. A call for participation was sent to centers contributing to the European/International FMD Registry.

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Aims: Fibromuscular dysplasia (FMD) and spontaneous coronary artery dissection (SCAD) are related, non-atherosclerotic arterial diseases mainly affecting middle-aged women. Little is known about their physiopathological mechanisms. We aimed to identify rare genetic causes to elucidate molecular mechanisms implicated in FMD and SCAD.

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Article Synopsis
  • - The European/International Fibromuscular Dysplasia (FMD) Registry has enrolled 1,022 patients from 22 countries since December 2015, primarily focusing on their characteristics by disease subtype, age, and gender.
  • - The study found that the majority of patients were women (82%), with key findings like 86% being hypertensive, and a distinction in profiles between multifocal and focal FMD cases, particularly regarding gender, age, and prevalence of related complications.
  • - Independent predictors for more severe forms of FMD, such as multivessel presence and risk of aneurysms or dissections, were identified, highlighting the need for targeted screening and management strategies for affected patients.
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Objective: Structural abnormalities in resistance arteries are a hallmark of patients with hypertension. In hypertensive patients with pheochromocytoma or paraganglioma (PPGL), it is still a matter of debate whether structural vascular changes are because of elevated blood pressure (BP) or to toxic effects of elevated circulating catecholamines. Hence, the aim of our study was to assess whether catecholamine excess and/or elevated BP affect the structure of small retinal arteries in patients with catecholamine-producing tumors.

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Fibromuscular dysplasia (FMD), regarded as a generalized vascular disease, may affect all vascular beds and may result in arterial stenosis, occlusion, aneurysm, or dissection. It has been proposed to systematically evaluate all vascular beds in patients with FMD, regardless of initial FMD involvement. However, the impact of this approach on clinical decisions and on management is unknown.

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Objective: Visceral artery fibromuscular dysplasia (VA FMD) manifestations range from asymptomatic to life-threatening. The aim of the study is to evaluate the prevalence and clinical characteristics of VA FMD.

Methods: A total of 232 FMD patients enrolled into ongoing ARCADIA-POL study were included in this analysis.

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The association between fibromuscular dysplasia (FMD) and spontaneous cervical artery dissection (SCeAD) has been recognized, but the available evidence on this relationship is scant. Therefore, the main goal of our study was to systematically evaluate FMD frequency, clinical characteristics and vascular bed involvement in patients with SCeAD. Among 230 patients referred to the ARCADIA-POL study, 43 patients (mean age 44.

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Nearly ten years ago percutaneous renal denervation (RDN) was introduced in clinical trials as a possible method of interventional treatment of resistant hypertension. The promising results of the first clinical trials initiated the intensive development of this method. However, the role of percutaneous renal denervation in the treatment of patients with resistant hypertension has been questioned since the results of the Symplicity HTN-3 trial have been published.

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Purpose: Smoking was identified as a potential factor contributing to fibromuscular dysplasia (FMD). To evaluate the prevalence of smoking and clinical characteristics in FMD subjects.

Material And Methods: We analysed 190 patients with confirmed FMD in at least one vascular bed.

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