Publications by authors named "Ewa Swieszkowska"

Article Synopsis
  • Rhabdomyosarcoma (RMS) of the biliary tract is a rare pediatric cancer, accounting for only 0.5-0.8% of all RMS cases in children, yet it is the most common malignancy in this area for that age group.
  • The study analyzed the medical records of eight children treated for biliary tract RMS between 1996-2022, focusing on symptoms, diagnoses, treatment approaches, and outcomes.
  • Among the patients, initial symptoms included jaundice, with treatment involving biopsy, chemotherapy, and surgery; 75% of the patients are currently alive with no disease progression after a median follow-up of over 11 years.
View Article and Find Full Text PDF

The aim of this study was to assess the long-term results of liver transplantation (LT) in pediatric patients with unresectable hepatoblastoma (HB) or hepatocellular carcinoma (HCC) with special reference to the risk of tumor recurrence. We retrospectively analyzed data from 46 HB and 26 HCC patients who underwent LT between 1990 and 2022. In HCC patients, we compared outcomes depending on donor type.

View Article and Find Full Text PDF

Craniospinal irradiation (CSI) has been a major component of the standard of care treatment backbone for childhood medulloblastoma. However, chemotherapy regimens have varied based on protocol, patient age, and molecular subtyping. In one of the largest studies to date, we analyzed treatment outcomes in children with newly-diagnosed medulloblastoma treated with pre-irradiation chemotherapy followed by risk-adapted radiotherapy and maintenance chemotherapy.

View Article and Find Full Text PDF

The aim of this study was to evaluate the health status of children cured from hepatoblastoma. Forty-five patients with hepatoblastoma treated between 1996-2014 were assessed. The recorded data included sex, age at diagnosis, disease stage, treatment methods, time since diagnosis, and the evaluation of health status domains which included performance status, growth development, hearing, cardiovascular, skeletal, gastrointestinal, genitourinary, neurological, and hematological function.

View Article and Find Full Text PDF

Background: Undifferentiated embryonal sarcoma of the liver (UESL) represents less than 5% of all malignant hepatic tumors in childhood. It is considered an aggressive neoplasm with an unfavorable prognosis. The aim of this paper is to present a single center experience in the treatment of children with UESL.

View Article and Find Full Text PDF

Approximately 60 children aged 0-18 years are diagnosed of NBL each year in Poland. About 60% of all patients suffering from NBL have a chance for durable cure. Unfortunately the prognosis for patients within the high-risk group accounting for more than 50% of all NBL patients remains poor despite the introduction of more intensive chemotherapy regimens with radical surgery procedures and megachemotherapy with subsequent stem cell transplantation.

View Article and Find Full Text PDF

Background: The purpose of this study was to determine whether the SWI sequence may improve the MRI evaluation of hemosiderin deposits in the brain.

Case Report: We report a case of a 7-year-old girl after a total resection of a large tumor mass (ependymoma G II) located in the left hemisphere. Late complication of surgery was hemosiderosis of the brain diagnosed with SWI sequence.

View Article and Find Full Text PDF