Publications by authors named "Ewa Smukalska"

Objective: The aim of the present study was to describe the epidemiology and course of rotavirus infection in children hospitalized at the T. Browicz Provincial Hospital for Infectious Diseases in Bydgoszcz, Poland in 2014 year.

Introduction: Rotavirus infection is responsible for over 2 millions hospitalizations per year among children under 5 year old.

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Background: Perinatal HCV transmission appears to be an important cause of HCV in children. Treatment of chronic hepatitis C in young children is controversial because of spontaneous HCV clearance and possible adverse events.

Case Report: Vertical HCV genotype 1 infection was diagnosed in a 3-month-old infant.

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Unlabelled: Clostridium difficile (CD) is one of the main factors of nosocomial infections both in children and adults and the number these infections is still growing. There is an increasing number of community-associated CDAD and CDIs with no exposure to antibiotics. Tests for CD among children are not routinely conducted because of high rate of carrying (from 13 to 70% infants).

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Background: Treatment of hepatitis C virus (HCV) infection with interferon (IFN) and ribavirin (RBV) is associated with adverse events, which may affect the patient's adherence to the treatment regimen and the treatment efficacy.

Objectives: The aim of this study was to assess the sustained viral response (SVR) and interdependence between the haematological characteristics (leukocyte count, platelet count, and haemoglobin levels) in patients with chronic hepatitis C (CHC) infection during treatment with IFN and RBV.

Patients And Methods: We conducted a retrospective cohort study of 170 children with CHC infection who completed treatment with IFN-α and RBV.

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Budd-Chiari syndrome is a rare disease, caused by obstruction of the hepatic venous outflow at the level of either the large hepatic veins or (and) the subdiaphragm segment of the inferior vena cava. The hematological disorders (myeloproliferative disorders, factor V Leiden deficiency), tumor and chronic inflammatory diseases are the most frequent causes of BCS in Europe and North America. Two cases of BCS, recognized in 24 and 43 years old females with subacute and chronic forms of the disease are presented in this article.

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The results of retrospective analysis of 97 children treated at Observation and Liver Diseases Unit in Bydgoszcz between 1st Jun and 30th Jun 2006 because of retrovirus diarrhea were presented. Those results took the liver activity into consideration. The age of children with hypertransaminazemia was assessed--the duration, intensity and date of occurrence of hypertransaminazemia was taken into consideration.

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This report presents the difficulty in diagnosing of Hirschsprung disease in an 8-year-old girl admitted to hospital with an acute diarrhea. Authors underline that the definite diagnosis of disease is confirmed by a full-thickness rectal biopsy and findings that indicate an absence of ganglion cells.

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Otologic problems are infrequent in HIV patients. Authors present the case of chronic otitis media in the HIV infected child. The patient with significant hearing loss, and prolonged aural discharge, resistant to local and systemic antibiotic treatment was treated surgically.

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Malaria occurs in Poland sporadically. It is imported from endemic regions, exceptionally by children. Lack of knowledge of the clinical course may result in false diagnosis and fatal outcome of the disease.

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Unlabelled: The aim of the study was evaluation of serum IL-2 and sIL-2R concentration in children with chronic hepatitis B without previous treatment.

Material And Methods: Investigations were performed on sera from 27 children, 13 HBsAg and HBeAg positive (group I) and 14 HBsAg positive, HBeAg negative, anti-HBe positive (group II). Serum IL-2 and sIL-2R concentrations were detected with ELISA method.

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Chickenpox is self limiting disease, with potentially dangerous course. Chickenpox complications can evoke the necessity of hospitalization. Assess the types and courses of chickenpox complications in child patients hospitalized in Provincial Hospital of Infectious Diseases in Bydogoszcz between 1999 and 2003.

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