Incidence and mortality of bullous pemphigoid in north-east Poland (Podlaskie Province), 1999-2012: a retrospective bicentric cohort study.

Background: Bullous pemphigoid (BP) is the most frequently encountered autoimmune blistering disorder, affecting mainly elderly population. The aim of the study was to assess the incidence of BP in Podlaskie Province (north-east Poland) in 1999-2012, socio-demographic characteristics and mortality of patients with BP.

Methods: The number of newly diagnosed (in two regional hospitals) cases of BP per million inhabitants of the province in consecutive years was calculated and analysis of age, sex, and residency of patients performed.

[Genital herpes--epidemiological and clinical issue still of importance].

Genital herpes (gh) is one of the most frequent sexually transmitted diseases and the most frequent cause of genital ulcer diseases. Its etiological agent is herpes simplex virus type 1 (HSV-1) or 2 (HSV-2). The role of HSV-1 as a cause of gh is increasing, especially among adolescents in developed countries.