Publications by authors named "Ewa Mierzejewska"

The knowledge of physical activity (PA) recommended for pregnant women and practical application of it has positive impact on the outcome. Nevertheless, it is estimated that in high-income countries over 40% of pregnant women are insufficiently physically active. One of the reasons is insufficient knowledge pregnant women have about allowed effort during pregnancy and both recommended and not recommended physical activities.

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Background: The long-term consequences of prematurity are often not sufficiently recognized. To address this gap, a prospective cohort study, which is a continuation of the multicenter Polish study PREMATURITAS, was conducted, utilizing unique clinical data from 20 years ago.

Objective: The main goal was to evaluate lung function, detect any structural abnormalities using lung ultrasound, and assess psychological well-being in young adults born between 24 and 34 weeks of gestational age (GA).

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Objective: To assess changes in caesarean section (CS) rates in Europe from 2015 to 2019 and utilise the Robson Ten Group Classification System (TGCS) to evaluate the contribution of different obstetric populations to overall CS rates and trends.

Design: Observational study utilising routine birth registry data.

Setting: A total of 28 European countries.

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Article Synopsis
  • Dirofilaria repens is a zoonotic parasite affecting canines and other carnivores, with dogs serving as a primary reservoir and source of infection for mosquitoes.
  • A study analyzed 511 samples from seven wild carnivore species in Poland to detect the presence of this parasite, revealing a total prevalence of 3.13% and positive cases in several regions, particularly Masovia, which had the highest prevalence.
  • This research marks the first comprehensive examination of D. repens in wild hosts in Poland, identifying the first case in Eurasian badgers in the country and the second case in Europe.
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Subcutaneous dirofilariosis is a fast-spreading infection of dogs, and occasionally of other carnivores and humans. Several factors contribute to its spread, including climate change, which facilitates development and survival of Dirofilaria repens in the mosquito vector. Movement/relocation of infected definitive hosts (dogs) from endemic regions to non-endemic regions is another possible cause of local emergence and the presence of a wide variety of wild reservoirs of the parasite may also contribute to its spread.

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Associations between genetic variants and susceptibility to infections have long been studied in free-living hosts so as to infer the contemporary evolutionary forces that shape the genetic polymorphisms of immunity genes. Despite extensive studies of proteins interacting with pathogen-derived ligands, such as MHC (major histocompatilbility complex) or TLR (Toll-like receptors), little is known about the efferent arm of the immune system. Cytokines are signalling molecules that trigger and modulate the immune response, acting as a crucial link between innate and adaptive immunity.

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Unlabelled: Humans are transforming natural habitats into managed urban green areas and impervious surfaces at an unprecedented pace. Yet the effects of human presence on animal life-history traits are rarely tested. This is particularly true in cities, where human presence is often indissociable from urbanisation itself.

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Worldwide neonatal screening for congenital hypothyroidism (CH) is a gold standard of active surveillance in newborns. Prompt diagnosis, subsequent timely treatment implementation, and proper dosage of levothyroxine (L-T4) are crucial for normal growth and development, especially of the central nervous system. However, overtreatment may have a potential negative impact on further neurodevelopment.

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Ticks are important vectors of numerous pathogens of medical and veterinary significance. The aim of the current study was to determine the prevalence of spp. and s.

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Ornate dog tick, Dermacentor reticulatus is an important vector of Babesia canis, and Rickettsia spp. and other pathogens of veterinary and public health interest. The current study is the first to investigate the long-term changes in prevalence of these pathogens in expanding tick populations in Central Europe.

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Article Synopsis
  • Two populations of Dermacentor reticulatus ticks in Poland (Western and Eastern) are adapting to new environments based on available hosts, focusing on juvenile ticks collected from rodents in various regions.
  • The study involved trapping rodents over three years in different habitats to analyze the presence of juvenile ticks, revealing significant differences in tick population dynamics between the Eastern and Western regions.
  • Results showed that D. reticulatus was the most prevalent tick on rodents in the Eastern region, while its numbers were much lower in the Western region, indicating stable populations in the East and a notable gap area between tick populations.
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In recent years, a new focus of the relict tick Haemaphysalis concinna was discovered in Western Poland, near Wolsztyn, Greater Poland voivodeship. This species may play an important role in the circulation of pathogens of medical and veterinary importance. In the present study we tested 880 juvenile ticks collected from rodents, including 427 H.

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Background: Lyme borreliosis (LB) is the most common vector-borne disease in Europe. Monitoring changes in the prevalence of different Borrelia species in ticks may be an important indicator of risk assessment and of differences in pathogenicity in humans. The objective of our study was to assess the prevalence, co-infection and distribution of Borrelia and Babesia species in ticks removed from humans in a large sample collected during a study period of 4 years.

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Article Synopsis
  • Tick-borne diseases, particularly canine babesiosis, are becoming more significant in Poland due to an expanding population of the tick species Dermacentor reticulatus, which is split into Eastern and Western groups by a non-endemic area.
  • A three-year study (2016-2018) monitored these tick populations, revealing an average range expansion of 2.5-10 km per year along river basins and a decrease in distance between the two groups.
  • The incidence of canine babesiosis was low in Western Poland and the gap area, but significantly higher in Central and Eastern Poland, highlighting a strong geographical and temporal link between tick populations and disease outbreaks.
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Dirofilariasis is a fast-spreading disease of dogs and humans in Europe. We investigated whether Dirofilaria spp. have spread northwards in Europe, invading the Baltic countries.

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The red fox (Vulpes vulpes) is known to be a reservoir host of various vector-borne protozoan parasites. Yet, the impact of these parasitic infections on the health status of the red fox is unknown. In this study, we compared the prevalence of haemoprotozoa in juvenile and adult foxes from four regions in Poland.

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In the present study, we identified the ectoparasite communities of red foxes in three regions of Poland that encompassed two endemic regions for the occurrence of Dermacentor reticulatus, as well as a region that is free of this tick species ('gap' area). Our study sites were selected to enable the role of foxes as hosts for juvenile (nest dwelling) and adult (exophilic) D. reticulatus ticks to be determined, and to assess their contribution to the spread of this important vector of Babesia canis.

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Safe and efficient techniques for the live capture of carnivores are limited. In this study, we identified some of the factors that could affect the success of capturing red fox cubs with live capture traps (also known as cage traps). During a three-year period, we analysed 32 captures of 25 fox cubs (1.

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Background: Rodents constitute an important part of the diet of many carnivore species. This predator-prey food chain is exploited by helminth parasites, such as cestodes, whose larval stages develop in rodents and then mature to the adult stage in predators. The main aim of our study was to use molecular techniques for identification of cestode species recovered from both intermediate and definitive hosts, with a particular focus on the genus Mesocestoides.

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The results of local-regional advanced melanoma (stage III) management are still not satisfactory. Particularly, there is no personalized treatment in stage III melanoma patients due to the lack of useful classical pathological markers for prognostication of indolent or aggressive course of the disease. The aim of this study was to explore melanoma genomic landscape by means of the mutational profiling of 50 genes influencing carcinogenesis pathways in the randomly selected 93 kinase inhibitor-naïve (KI-naïve) stage III patients.

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Pregnancy is a period in life in which women are willing to improve their lifestyle. Providing proper information for these women is crucial for their health and the health of their offspring. Clear information about weak points in their nutritional and weight gain knowledge is the first step for proper health care assistance.

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Article Synopsis
  • This study aimed to compare the effectiveness of detecting Babesia species and Hepatozoon canis in blood versus faecal samples from infected hosts, noting the advantages of using non-invasive faecal sampling.
  • Using mice, dogs, and foxes as subjects, researchers extracted DNA from blood and faeces, employing PCR techniques for detection, achieving a 100% detection rate in mice but lower rates in dogs and foxes.
  • The findings suggest that while faecal sampling can aid in identifying Babesia infections when blood samples are hard to obtain, it may result in underestimating the true prevalence of these infections in natural populations.
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Introduction: Pseudomonas aeruginosa cross-infections are related to increased morbidity and mortality in cystic fibrosis (CF).

Objectives: The aim of the study was to evaluate the incidence of cross-infections with P. aeruginosa in children with CF.

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: So far no research concerning the omentin-1 ( rs2274907 and vaspin ( rs2236242 polymorphisms has been carried out in a healthy pediatric population. We analyzed associations of these polymorphisms with anthropometric parameters, lipid profile, as well as adiponectin, leptin and soluble leptin receptor (sOB-R) levels in prepubertal healthy children, to search for their possible role in the risk of obesity and obesity-related disorders.: Frequencies of these polymorphisms were analyzed by the restriction fragment length polymorphism in 89 normal-weight children.

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Juvenile Dermacentor reticulatus ticks inhabit nests and burrows of their rodent hosts and cannot be collected from vegetation. To detect vertical transmission of Babesia canis in D. reticulatus, we studied larvae and nymphs collected from rodents.

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