Oxidant-antioxidant balance in patients with psoriasis.

Background: Psoriasis is a chronic inflammatory skin disease characterized by pathological skin lesions due to various exogenous and endogenous factors and associated with a number of biochemical and immunological disturbances. Antioxidant enzymes may be involved in the pathogenesis of the disease. The aim of this study was to evaluate the concentration of lipid peroxidation products and glutathione peroxidase (GPx) activity in the blood of patients with psoriasis before and after treatment by conventional methods.