Aim: Assessment of frequency and clinical course of infections with herpesviruses: CMV, EBV, HHV-6 and HHV-7 in patients that underwent non-manipulated allo-HSCT from matched-related donors.
Methods: 35 recipients of age 31 +/- 8 years. Serological status of donor and recipient against CMV and EBV assessed before transplantation.
Objective: Assessment of frequency and clinical course of EBV infection in patients that underwent non-manipulated allo-HCT from matched-related donors.
Methods: Active EBV infection was confirmed based on the presence of anti-EA antibodies (ELISA) and/or viral DNA (nPCR) isolated from peripheral leukocytes. For positive DNA-isolations semi-quantitative analysis were done.