Publications by authors named "Evyapan G"
The skin is constantly exposed to a variety of environmental stressors, including ultraviolet (UV) radiation. Exposure of the skin to UV radiation causes a number of detrimental biological damages such as endoplasmic reticulum (ER) stress. The ER stress response is a cytoprotective mechanism that maintains homeostasis of the ER by increasing the capacity of the ER against the accumulation of unfolded proteins in the ER.
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- Non-small cell lung cancer (NSCLC) is the leading cause of cancer deaths worldwide, and current treatments are inadequate, highlighting the need for new therapies.
- Ornidazole, a drug primarily used for treating parasitic infections, was studied for its effects on NSCLC cells, showing promise in reducing cell viability, migration, and angiogenesis.
- The findings suggest Ornidazole could be an effective new treatment option for NSCLC by targeting the molecular pathways involved in tumor growth and spread.
Objective: The current study provides training to parents and teachers about pediculosis in schools in three villages in Adana to measure their knowledge level by conducting surveys and to determine the prevalence of pediculosis in these foci.
Methods: Pre- and post-questionnaires including 30 questions about pediculosis were handed to parents and teachers. The answers were analyzed with the Pearson correlation analysis.
Aim: To evaluate the inhibitory effects of ornidazole on the proliferation and migration of metastatic melanoma cell line (B16F10) in vitro and its anti-cancer effects in vivo using a melanoma mouse model.
Methods: We investigated the effects of ornidazole on cell viability (Crystal Violet and MTT assay) and migration ability (wound-healing assay) of B16F10 melanoma cells, and its ability to trigger DNA damage (Comet assay) in vitro. We also sorted CD133+ and CD133- cells from B16F10 melanoma cell line and injected them subcutaneously into Swiss albino mice to induce tumor formation.
Article Synopsis
- About half of childhood and adolescent cases of obsessive-compulsive disorder (OCD) have symptoms that persist into adulthood, and a study suggests that immunologic stress may increase the risk of developing OCD in childhood.
- Researchers analyzed the MHC complex I and II alleles in 49 children with OCD and 277 healthy peers, using various statistical methods to interpret their findings.
- The study identified specific alleles (A2, A29, C4, DRB3.1, and DRB1*16) that are associated with a higher risk of developing OCD, and it highlights a potential link between MHC genes and OCD that reflects similar associations found in autoimmune disorders.
The aim of this study is to compare the presence of Trichomonas vaginalis (T. vaginalis) in symptomatic and asymptomatic women through microscopic examination, culture in Trypticase-Yeast Maltose (TYM) medium and PCR methods. In addition, T.
View Article and Find Full Text PDFLeishmaniasis, presenting in two clinical forms, cutaneous and visceral in Turkey, is widespread in most of the countries in the Mediterranean Basin. An average of 10 to 13% of cases are reported from Adana every year. This paper presents the results of an entomological survey in an endemic focus of cutaneous leishmaniasis in Imamoglu province of Adana in Turkey.
View Article and Find Full Text PDFGenotyping of Acanthamoeba T15: the environmental strain in Turkey.
Trans R Soc Trop Med Hyg
March 2015
Background: Environmental sources are potential sources for the transmission of Acanthamoeba in humans and other mammals.
Methods: A total of 50 water samples from hot springs and swimming pools, and 50 soil samples were taken from Adana, Afyon, Kutahya, Mersin and Nigde provinces in Turkey. Samples were analysed using 18S rRNA-DNA sequencing.