Which is the best technique for endometrial sampling? Aspiration (pipelle) versus dilatation and curettage (D&C).

Purpose: To compare diagnostic accuracy and adequacy of pipelle endometrial biopsy with dilatation and curettage.

Methods: From October 2007 to November 2009, 673 patients were evaluated with pipelle endometrium biopsy, D&C and hysterectomy in the Department of Obstetrics and Gynecology, Istanbul University Cerrahpasa Medical Faculty. 478 patients underwent pipelle and D&C, 212 patients underwent pipelle and hysterectomy and 161 patients underwent D&C and hysterectomy.