A Deeper Insight into , , and Variants and Genotype-Phenotype Correlation of a Turkish Cohort with Alport Syndrome.

Introduction: Alport syndrome (AS) is an inherited, rare, progressive kidney disease that affects the eye and ear physiology. Pathogenic variants of account for 85% of all cases, while and account for the remaining 15%.

Methods: Targeted next-generation sequencing of the , , and genes was performed in 125 Turkish patients with AS.

Whole-Exome Sequencing (WES) results of 50 patients with chronic kidney diseases: a perspective of Alport syndrome.

Objective: Chronic kidney disease (CKD) remains one of the major common health problems, and the number of people affected by the disease is progressively increasing in Turkey and worldwide. This study aimed to investigate molecular defects in Alport syndrome (AS) and other genes in patients with clinically suspected CKD using whole-exome sequencing (WES).

Methods: Patients with clinical suspicion of CKD were included in the study.

Exposure of married women to spousal violence: A community-based study in Eastern Turkey.

Background: Violence against women deprives women of their rights to enjoy equality, security, dignity, self-worth and fundamental freedoms and devalues them; is one of the most significant social facts that force women to exist at a lower social level than men and constitute a significant obstacle to the formation of healthy societies. This study was conducted to determine the status of exposure to spousal violence of 15 years and older married women living in the city center.

Methods: Family health centers in Elazig Province were visited and 792 married women were selected from the related records by systematic sampling.

Social gender and nursing in Turkey: A qualitative research.

Although the Turkish women have a much better position in terms of jobs and education, they still assume the roles expected by the society, despite all the changes that have taken place in today's Turkey, which continues to have a patriarchal society structure. Working did not change women's roles of homemaking and motherhood in the family; instead, their burden in social life has increased. Nursing in Turkey has been regarded as a women's profession for many years and has only been performed by women until the last decade.

Chemical, biological and molecular modelling analyses to probe into the pharmacological potential of Antidesma madagascariense Lam.: A multifunctional agent for developing novel therapeutic formulations.

Antidesma madagascariense Lam. (AM), an indigenous medicinal plant to the Mascarene Islands, is used for the treatment of several diseases. We endeavoured to validate its use via evaluating the kinetics of inhibition of crude aqueous extract (CAE) and crude methanol extract (CME) of AM against key metabolic enzymes (pancreatic lipase, cholesterol esterase [CEase], acetylcholinesterase [AChE], and urease).

Identification of the drug-use behaviors of the elderly living in nursing homes.

Objective: As our society ages, the incidence of acute and chronic diseases increases, and so does chronic drug use and polypharmacy. This study was intended to examine the medication behaviors of the elderly who lived in the nursing homes in the Elazig and Malatya provinces, located in eastern Turkey, and in the Kayseri province located in Central Anatolia.

Materials And Methods: The population of this cross-sectional study included people over the age of 60 years (n=310) who lived in the nursing homes in the Elazig, Malatya, and Kayseri provinces.