Publications by authors named "Evgenya Dobronevsky"
Article Synopsis
- Purpose: The study investigates the long-term effects of combining repetitive transcranial magnetic stimulation (rTMS) with cognitive training on brain activity in Alzheimer’s disease (AD) patients, since existing medications have limited impact on slowing cognitive decline.
- Methods: Researchers measured brain electrical activity (EEG) in seven mild AD patients before treatment and after each session during 54 treatment sessions over 4.5 months to assess the effects of rTMS and cognitive training.
- Results: After treatment, there was a significant increase in brain activity (delta) in the temporal region, along with various nonsignificant changes in other brain wave patterns, suggesting potential benefits; higher alpha activity correlated positively with cognitive performance over time,
Background: The search for biomarkers in Parkinson's disease (PD) is crucial to identify the disease early and monitor the effectiveness of neuroprotective therapies. We aim to assess whether a gene signature could be detected in blood from early/mild PD patients that could support the diagnosis of early PD, focusing on genes found particularly altered in the substantia nigra of sporadic PD.
Results: The transcriptional expression of seven selected genes was examined in blood samples from 62 early stage PD patients and 64 healthy age-matched controls.