Publications by authors named "Evgeny Voronin"
Outcomes of etravirine-based antiretroviral treatment in treatment-experienced children and adolescents living with HIV in Europe and Thailand.
Antivir Ther
June 2022
Article Synopsis
- Etravirine (ETR) is used for second or third-line antiretroviral treatment in children with HIV, and a study assessed its outcomes in children across Europe and Thailand.
- Data was collected from 177 children, showing that 69% achieved viral suppression after 12 months and experienced an increase in CD4 cell counts; however, 46% discontinued ETR due to reasons such as treatment simplification and failure.
- Some adverse events were reported, including rare but serious reactions like Stevens-Johnson Syndrome, but overall, ETR proved effective for many treatment-experienced children.
Article Synopsis
- Bictegravir combined with emtricitabine/tenofovir alafenamide (B/F/TAF) is an effective and well-tolerated HIV treatment, showing no resistance in treatment-naive and suppressed patients for 48 weeks.* -
- In a phase 3 trial, 472 women with suppressed HIV were randomly assigned to either switch to B/F/TAF or continue their current regimen, with results demonstrating that switching was as effective as staying on the original treatment.* -
- The study highlights B/F/TAF as a safe option for women living with HIV, providing essential insights into the efficacy and tolerability of antiretroviral therapy specifically for this group.*
Background: Women are under-represented in HIV antiretroviral therapy (ART) studies. Guidelines for selection of ART as initial therapy in patients with HIV-1 infection do not contain sex-specific treatment. We aimed to assess the safety and efficacy of the single tablet integrase inhibitor regimen containing elvitegravir, cobicistat, emtricitabine, and tenofovir disoproxil fumarate compared with a boosted protease inhibitor regimen of ritonavir-boosted atazanavir with emtricitabine and tenofovir disoproxil fumarate.
View Article and Find Full Text PDFBackground: The HIV epidemic in Russia has increasingly involved reproductive-aged women, which may increase perinatal HIV transmission.
Methods: Standard HIV case-reporting and enhanced perinatal HIV surveillance systems were used for prospective assessment of HIV-infected women giving birth in St. Petersburg, Russia, during 2004-2008.
Objective: The purpose of this study was to evaluate the effectiveness of a human immunodeficiency virus (HIV) rapid testing (RT) program.
Study Design: From April 13, 2004, to April 13, 2005, pregnant women at 2 high-risk maternity hospitals with no or incomplete HIV testing results (negative tests at <34 weeks, none thereafter) were offered point-of-care RT, with antiretroviral prophylaxis for RT-positive women and their infants.
Results: Overall, 89.
In St Petersburg, Russia, a rapid HIV-testing programme was implemented in April 2004 for high-risk women giving birth. Among 670 women without prenatal care who received rapid HIV testing, 6.4% (43) had positive results.
View Article and Find Full Text PDFQuality of life of mothers having nosocomially HIV-infected children in Russia.
Disabil Rehabil
October 2003
Background: 274 children were HIV-infected during 1988-89 in hospitals in the South of Russia during treatment of heavy pathology requiring an intensive therapy and catheterization of large venous vessels. Today only 140 children, receiving HAART now, remain alive.
Patients And Methods: In 1988 - 89 mothers having nosocomially HIV-infected children were tested on a 'WHOQOL-100' technique (Russian version).