Publications by authors named "Evgeny Sozontov"

Purpose: An intensity-modulated X-ray brachytherapy system is being developed for various clinical applications. This new system makes it possible for clinical staff to control energy as well as dose rate for different tumor sites according to their sizes and radiobiological characteristics.

Materials And Methods: This system is mainly composed of an X-ray tube, guide tube collimation, and secondary (pseudo) target.

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Magnetite nanoparticles possess several properties that can make them useful for targeted delivery of radiation to tumors for the purpose of brachytherapy. Such particles are biodegradable and magnetic and can emit secondary radiation when irradiated by an external source. In this work, the dose distribution around a magnetite particle of 10 nm diameter being irradiated by monochromatic X-rays with energies in the range 4-60 keV is calculated.

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The basic design and performance of a novel x-ray scalpel device for interstitial radiosurgery are reported. The x-ray scalpel is comprised of a capillary optics collimator conjugated with a high brilliance microfocus x-ray tube and a thin hollow needle (tip) attached to the collimator. The device is capable of producing a high dose rate (about 140 Gy min(-1) in water-like absorber at the exit window), 0.

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