Mitochondrial dependent oxidative stress in cell culture induced by laser radiation at 1265 nm.

Photodynamic therapy is the main technique applied for surface carcinoma treatment. This technique employs singlet oxygen generated via a laser excited photosensitizer as a main damaging agent. However, prolonged sensitivity to intensive light, relatively low tissue penetration by activating light the cost of photosensitizer (PS) administration can limit photodynamic therapy applications.

Waveguide-saturable absorber fabricated by femtosecond pulses in YAG:Cr(4+) crystal for Q-switched operation of Yb-fiber laser.

A waveguide-saturable absorber with low propagation loss is fabricated by femtosecond pulses in YAG:Cr(4+) crystal. Q-switch operation of a Yb fiber laser with the new saturable absorber having absorption saturation parameters similar to the bulk YAG:Cr(4+) crystal is demonstrated.