Danon Disease: Entire Gene Deletion with Unusual Clinical Presentation-Case Report and Review of the Literature.

Danon disease is a rare x-linked dominant multisystemic disorder with a clinical triad of severe cardiomyopathy, skeletal myopathy, and intellectual disability. It is caused by defects in the lysosome-associated membrane protein-2 () gene. Numerous different mutations in the protein have been described.

The impact of left ventricular ejection fraction on heart failure patients with pulmonary hypertension.

Background: The most common cause of pulmonary hypertension (PH) in developed countries is left heart disease (LHD, group 2 PH). The development of PH in heart failure (HF) patients is indicative of worse outcomes.

Objective: The aim of this study was to evaluate the long term outcomes of HF patients with PH in a national long-term registry.