Publications by authors named "Evgeniya Bederina"

Article Synopsis
  • - The study introduces a new use of compression optical coherence elastography (C-OCE) to track damage in small intestine layers of minipigs (n = 36) as they are stretched.
  • - C-OCE measured the stiffness of different intestine wall layers and identified a significant drop in stiffness in the longitudinal muscular layer at 25% elongation, indicating potential tears.
  • - The results suggest that C-OCE could effectively predict safe stretching limits of intestinal tissues, which could be crucial for preventing ruptures during medical procedures.
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(1) Introduction. The problem that limits the intraoperative use of OCTA for the intestinal circulation diagnostics is the low informative value of OCTA images containing too many motion artifacts. The aim of this study is to evaluate the efficiency and safety of the developed unit for the prevention of the appearance of motion artifacts in the OCTA images of the intestine in both open and laparoscopic surgery in the experiment; (2) Methods.

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Development of the novel diagnostic and therapeutic approaches in neuro-oncology requires tumor models that closely reproduce the biological features of patients' tumors. Patient-derived xenografts (PDXs) are recognized as a valuable and the most "close-to-patient" tool for preclinical studies. However, their establishment is complicated by the factors related to both the surgical material and technique of the orthotopic implantation.

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Introduction: Despite the introduction of increasingly multifaceted diagnostic techniques and the general advances in emergency abdominal and vascular surgery, the outcome of treatment of patients with acute impaired intestinal circulation remains unsatisfactory. The non-invasive and high-resolution technique of optical coherence tomography (OCT) can be used intraoperatively to assess intestine viability and associated conditions that frequently emerge under conditions of impaired blood circulation. This study aims to demonstrate the effectiveness of multimodal (MM) OCT for intraoperative diagnostics of both the microstructure (cross-polarization OCT mode) and microcirculation (OCT angiography mode) of the small intestine wall in patients with acute mesenteric ischemia (AMI).

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