DNA topoisomerase I alpha is required for adaptive response to light and flower development.

DNA topoisomerase I alpha (TOP1α) plays a specific role in development and is required for stem cell regulation in shoot and floral meristems. Recently, a new role independent of meristem functioning has been described for TOP1α, namely flowering time regulation. The same feature had been detected by us earlier for , a mutant allele of In this study we clarify the effects of on bolting initiation and analyze the molecular basis of its role on flowering time regulation.