Publications by authors named "Evgeniy Elisaphenko"

Thirty-four isolates of Metarhizium spp. from Russian collections were genotyped using 5' EF-1α gene sequence analysis. Four species were identified, of which M.

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MicroRNAs (miRNAs) constitute a class of small noncoding RNAs that plays an important role in the post-transcriptional regulation of gene expression. Much evidence has demonstrated that miRNAs are involved in regulating the human and mouse pluripotency. Nevertheless, to our knowledge, miRNAs in the pluripotent stem cells of one of the most commonly used model organisms - the Rattus norvegicus have not been studied.

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Article Synopsis
  • Rat pluripotent stem cells, including embryonic (ESCs) and induced pluripotent stem cells (iPSCs), show promise for research on early mammalian development, but data on rat pluripotency and differentiation methods are limited.
  • The study utilized RNA-Seq to analyze the transcriptomes of rat ESCs and iPSCs, revealing that they are quite similar and distinct from differentiated cells, along with a notable X-chromosome reactivation during reprogramming.
  • A new monolayer differentiation protocol was developed to better understand X-chromosome inactivation dynamics and facilitate the creation of specific cell types for biomedical applications.
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