Publications by authors named "Ever A Corral-Herrera"
Background: This case series of 5 patients with severely necrotic mpox highlights the predominantly necrotic nature of lesions seen in cases of severe mpox as shown by skin and lung biopsy, as well as the extensive dissemination of the infection, as shown by polymerase chain reaction (PCR) assessment in different body sites.
Case Presentations: Patients were male, the median age was 37, all lived with HIV (2 previously undiagnosed), the median CD4 cell count was 106 cells/mm, and 2/5 were not receiving antiretroviral treatment. The most common complication was soft tissue infection.
Article Synopsis
- Invasive Fungal Infections (IFI) are emerging complications in critically ill COVID-19 patients, with a prevalence of 9.3% found in this study.
- The study, conducted in an ICU, identified related factors influencing IFIs, such as higher SOFA scores and the use of empirical antibiotics, particularly in cases of COVID-19-associated pulmonary aspergillosis (CAPA).
- Despite a high prevalence of IFIs and significant mortality rates, there was no mortality difference observed among patients with these infections compared to matched controls.
Article Synopsis
- A significant portion of the 2022 mpox outbreak involved individuals with HIV, particularly those with low CD4 cell counts, suggesting the need to understand their clinical outcomes.
- Data from a network of clinicians across 19 countries was analyzed, focusing on adults living with HIV and CD4 counts below 350 cells per mm to assess their presentation and complications from mpox.
- Out of 382 cases analyzed, most individuals were men, with a median age of 35, and those with CD4 counts under 100 cells per mm experienced more severe complications, highlighting the risks associated with advanced HIV.
CLINICAL AND EPIDEMIOLOGICAL CHARACTERISTICS OF PATIENTS DIAGNOSED WITH COVID-19 IN A TERTIARY CARE CENTER IN MEXICO CITY: A PROSPECTIVE COHORT STUDY.
Rev Invest Clin
January 2020
CLINICAL AND EPIDEMIOLOGICAL CHARACTERISTICS OF PATIENTS DIAGNOSED WITH COVID-19 IN A TERTIARY CARE CENTER IN MEXICO CITY: A PROSPECTIVE COHORT STUDY.
Rev Invest Clin
July 2020
Background: Regional information regarding the characteristics of patients with coronavirus disease (COVID)-19 is needed for a better understanding of the pandemic.
Objective: The objective of the study to describe the clinical features of COVID-19 patients diagnosed in a tertiary-care center in Mexico City and to assess differences according to the treatment setting (ambulatory vs. hospital) and to the need of intensive care (IC).