Publications by authors named "Evelyn-Laura Bielefeld"
Microorganisms
February 2021
Article Synopsis
- Carbon catabolite repression (CCR) is a mechanism that helps pathogenic bacteria connect their energy processing to the production of factors that help them cause disease.
- In gram-positive bacteria, CcpA and the HPr protein are key players in regulating CCR, with HPr being crucial for glucose uptake.
- Research involving mutants of HPr showed that it significantly impacts bacterial growth, biofilm formation, and infection ability, indicating that HPr influences metabolism and virulence beyond just its role in regulating CcpA.
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