Publications by authors named "Evelyn Owusu-Mireku"
Background: Buruli ulcer (BU), a necrotizing skin infection caused by Mycobacterium ulcerans is the third most important mycobacterial disease globally after tuberculosis and leprosy in immune competent individuals. This study reports on the retrospective analyses of microbiologically confirmed Buruli ulcer (BU) cases in seventy-five health facilities in Ghana.
Method/principal Findings: Pathological samples were collected from BU lesions and transported either through courier services or by car directly to the laboratory.
Article Synopsis
- A new study focuses on the CA-MRSA strain ST88, which is rapidly becoming common in Africa, particularly in Ghana, where its genetic background is investigated using whole genome sequencing.
- Researchers successfully established a reference genome and compared 17 Ghanaian ST88 isolates with other MRSA strains, revealing that Ghanaian ST88 forms a distinct lineage with unique genomic features.
- The study highlights ST88-IV's rapid spread and antibiotic resistance, emphasizing the importance of genomic assessments in public health, especially in resource-limited areas.
The synergy between Mycobacterium tuberculosis infection and human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome is well established but not so in Buruli ulcer (BU). We screened confirmed BU cases for HIV infection and followed seven BU/HIV-coinfected patients. Management of BU/HIV was based on the World Health Organization guidelines and patient condition.
View Article and Find Full Text PDFBuruli ulcer (BU), caused by Mycobacterium ulcerans is a chronic necrotizing skin disease. It usually starts with a subcutaneous nodule or plaque containing large clusters of extracellular acid-fast bacilli. Surrounding tissue is destroyed by the cytotoxic macrolide toxin mycolactone produced by microcolonies of M.
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