Publications by authors named "Evelyn Luna"
Article Synopsis
- Cutaneous mixed tumors are categorized into apocrine and eccrine types, with apocrine tumors commonly featuring a unique plasmacytoid myoepithelial component, particularly in hyaline cell-rich types.
- This study analyzed 41 cases, revealing that apocrine tumors frequently exhibited PLAG1 and HMGA2 fusions, while eccrine tumors showed distinct SOX10 internal duplications through RNA sequencing.
- Clustering analysis highlighted the genetic differences across tumor types, confirming a unique profile for eccrine mixed tumors and establishing relationships among various tumor types, contributing to a deeper understanding of their molecular characteristics.
Aims: Poroma is a benign adnexal neoplasm with differentiation towards the upper portion of the sweat gland apparatus. In 2019, Sekine et al. demonstrated recurrent YAP1::MAML2 and YAP1::NUTM1 fusion in poroma and porocarcinoma.
View Article and Find Full Text PDFSolid cancers that metastasize to the lungs represent a major therapeutic challenge. Current treatment paradigms for lung metastases consist of radiation therapy, chemotherapies, and surgical resection, but there is no single treatment or combination that is effective for all tumor types. To address this, oncolytic myxoma virus (MYXV) engineered to express human tumor necrosis factor (vMyx-hTNF) was tested after systemic administration in an immunocompetent mouse K7M2-Luc lung metastatic osteosarcoma model.
View Article and Find Full Text PDFArticle Synopsis
- Primary health care (PHC) nursing in the Philippines is under-researched, despite its widespread practice, and this paper highlights a specific PHC nursing curriculum on a southern island.
- The study collected data from faculty nurses who balance teaching and community service, using phenomenological analysis to uncover their experiences.
- Four main themes emerged from the data: teaching PHC, external influences, the working reality, and practicing PHC, revealing critical insights about educational and clinical challenges in this model, along with recommendations for future research.