Publications by authors named "Evelyn Ketty Pratt Riccio"
Plasmodium vivax metacaspase 1 (PvMCA1) catalytic domain is conserved in field isolates from Brazilian Amazon.
Hugo Amorim Dos Santos de Souza Victor Fernandes Escafa Carolina Moreira Blanco Bárbara de Oliveira Baptista Jenifer Peixoto de Barros Evelyn Ketty Pratt Riccio Lilian Rose Pratt-Riccio
Mem Inst Oswaldo Cruz
June 2021
Article Synopsis
- The study examined genetic diversity in Plasmodium vivax metacaspase 1 (PvMCA1) in Brazil's Juruá Valley, finding the complete genetic sequence identical among field isolates and a reference strain.
- Analysis of PvMCA1 across different global genomic sequences showed high conservation, with very few changes to critical amino acids related to its catalytic function.
- The genetic stability of PvMCA1 suggests it could be a viable target for drug development against vivax malaria.