Publications by authors named "Eveline A M Bouwens"
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Synopsis of recent research by authors named "Eveline A M Bouwens"
- Eveline A M Bouwens' research primarily focuses on the interaction and functional roles of coagulation factors, particularly Factor VIII and the Protein C system, in endothelial cells and their implications in conditions such as hemophilia and malaria.
- The findings highlight the discrete C-domain roles of Factor VIII in its function and intracellular trafficking, revealing mechanisms behind von Willebrand factor binding and the storage and release dynamics in Weibel-Palade bodies.
- Additionally, research on the endothelial protein C receptor (EPCR) demonstrates its pivotal role in the anticoagulant and cytoprotective effects of the Protein C system, significantly influencing vascular health and responses during inflammatory diseases.
