Evaluation of a New Automated Mono-Test for the Detection of Galactomannan: Comparison of Galactomannan Ag VirCLIA Mono-Test with Platelia Ag ELISA Assay.

The analytical performance of the new Galactomannan Ag VirCLIA mono-test (Vircell S.L.) was compared to the Platelia™ Ag ELISA assay (Bio-Rad).

[Clinical trials approved by Aifa for Covid-19: report of the main results to fill the unmet medical need.].

Introduction: the rapidity with which the Coronavirus epidemic emergency exploded took the scientific community by surprise, unprepared for such an event. The objective of this work is to evaluate, to date, the state of the art of the clinical trials approved by Aifa, analyzing the characteristics of the single completed and published trials and the authorization status for the use of the drugs under study in the treatment of Covid-19.

Materials And Methods: The protocols available for each clinical study were extrapolated from the Aifa website relating to the management of clinical trials in Italy during the Covid-19 emergency; the unique EudraCT and Nct codes were extrapolated from these, verifying their publication using the PubMed search engine, the ClinicalTrials.

Emilia-Romagna Regional Blood System accreditation as an example of improvement through application of specific requirements: a retrospective analysis.

Background: Institutional accreditation in Italy represents the license given by a region to a public or private facility to provide services in the name and on behalf of the National Health Service. This study aims to evaluate the improvement of the Emilia-Romagna Regional Blood System and to highlight its unresolved issues, analysing non-conformities observed during accreditation and maintenance inspections between 2013 and 2018.

Methods: All the Emilia-Romagna Regional Blood facilities were invited to participate in this study voluntarily and anonymously.

COVID-19 Outbreak in Italy: Report on the First 124 Consecutive Patients Treated at Home.

North Italy emerged as an epicenter of COVID-19 in the Western world. The majority of studies of patients with COVID-19 have focused on hospitalized patients, and data on early outpatient treatment are limited. This research retrospectively examines consecutive symptomatic adults who did not present to a hospital but who experience laboratory confirmed (nasopharyngeal swabs) or probable COVID-19 infection.

Cancer patients with COVID-19: a retrospective study of 51 patients in the district of Piacenza, Northern Italy.

Background: Cancer patients are considered a highly fragile group in the current coronavirus disease 2019 (COVID-19) pandemic.

Material & Methods: In this study, patients with COVID-19 and cancer, hospitalized in Piacenza, Italy, from 4 April to 4 May 2020 were included. Risk factors for death were analyzed.

Insulin-like growth factor 1 as a predictor of ischemic stroke outcome in the elderly.

Purpose: To examine whether serum insulin-like growth factor 1 (IGF-1) and IGF binding protein 3 (IGFBP-3) concentrations, determined early after the onset of stroke, are predictive of clinical outcome in elderly patients.

Methods: The sample comprised 85 patients (mean [+/- SD] age, 83 +/- 7.4 years; range, 67 to 99 years; 34% male) who were admitted with acute stroke to a geriatric ward between January 1998 and June 2000, and 88 control patients who were similar in age and sex.