Publications by authors named "Evans K Ahortor"
Article Synopsis
- - Buruli ulcer (BU) is a severe skin disease caused by Mycobacterium ulcerans, and diagnosing it typically relies on PCR methods, which can be challenging in remote areas due to equipment needs; LAMP is proposed as a simpler diagnostic alternative.
- - This study aims to compare a rapid DNA extraction method using a syringe with a conventional approach, followed by a LAMP assay, and to assess the diagnostic workflow in a rural Ghanaian health center through interviews with health professionals.
- - The results indicated that the syringe-based extraction method successfully detected MU DNA in a significant number of cases with high sensitivity and specificity, while the LAMP assay also showed promising results but with varying predictive values depending on the method of DNA extraction
Identifying the source reservoirs of Mycobacterium ulcerans is key to understanding the mode of transmission of this pathogen and controlling the spread of Buruli ulcer (BU). In Australia, the native possum can harbor M. ulcerans in its gastrointestinal tract and shed high concentrations of the bacteria in its feces.
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