A Triangular Frustrated Eu(II)-Organic Framework for Sub-Kelvin Magnetic Refrigeration.

Attaining sub-Kelvin temperatures remains technologically challenging and often relies on the scarce resource He, unless employing adiabatic demagnetization refrigeration. Herein, the active coolant typically consists of weakly coupled paramagnetic ions, whose magnetic interaction strengths are comparable in energy to the relevant temperature regime of cooling. Such interactions depend strongly on inter-ion distances, fundamentally hindering the realization of dense coolants for sub-Kelvin refrigeration.

Magnetocaloric effect in a high-spin ferromagnetic molecular cluster.

The reaction of MnCl·4HO with HL ((1-methyl-1H-imidazol-2-yl)methanol) and pdH (1, 3 propanediol) in a basic MeCN solution results in the formation of a mixed-valence [Mn] cationic cluster and two [MnCl] counter anions. The metallic skeleton of the cluster describes two geometrically equivalent mixed-valent, linked [Mn Mn ] supertetrahedra in which nearest-neighbor metal ions have a different oxidation state. Magnetic susceptibility, magnetization data and heat capacity measurements support evidence of predominant ferromagnetic correlations, leading to a = 22 spin ground state for the [Mn Mn ] supertetrahedra, which are pair-linked by a weak antiferromagnetic coupling.

Stellated cuboctahedron of Fe.

The solvothermal reaction of FeCl ⋅ 4HO and HTBC[4] in a basic dmf/EtOH solution affords an [Fe ] Keplerate conforming to a stellated cuboctahedron. Magnetic and heat capacity measurements reveal spin frustration effects arising from the high symmetry. A crossover between inverse and direct magnetocaloric effects is observed at ~10 K for applied-field changes lower than 3 T.

Ocular endothelial dysfunction in pediatric inflammatory bowel disease.

Objectives: To assess ocular microvasculature changes using optical coherence tomography angiography (OCTA) in pediatric patients with inflammatory bowel disease (IBD).

Methods: Patients (aged 6-18 years) with IBD were recruited between September 2021 and May 2023. All eligible participants underwent comprehensive clinical assessment and laboratory investigation.

Palmitoylethanolamide and polydatin in pediatric irritable bowel syndrome: A multicentric randomized controlled trial.

Objective: This study aimed to evaluate the efficacy and safety of co-micronized palmitoylethanolamide (PEA)/polydatin (PD) in the treatment of abdominal pain symptoms in pediatric patients with irritable bowel syndrome (IBS).

Methods: This was a multicenter trial conducted at three Italian pediatric gastroenterology centers, employing a double-blind, placebo-controlled, parallel-arm design. Participants were ages 10 to 17 y and met Rome IV criteria for pediatric IBS.

Within-breath oscillometry for identifying exercise-induced bronchoconstriction in pediatric patients reporting symptoms with exercise.

Background: Evaluating oscillometry parameters separately for the inspiratory and expiratory breath phases and their within-breath differences can help to identify exercise-induced bronchoconstriction (EIB) in pediatric outpatients disclosing exercise-induced symptoms (EIS).

Aims: To assess the response in impedance parameters following an exercise challenge in patients reporting EIS.

Methods: Sixty-eight patients reporting EIS (34 asthmatics and 34 suspected of asthma, age mean = 10.

Oxidative stress and optical coherence tomography angiography evaluation of choriocapillaris and retinal vessel density in children with obstructive sleep apnea.

Objectives: To investigate the vascular networks of the retina and choroid using optical coherence tomography angiography (OCTA) to identify early biomarkers of obstructive sleep apnea (OSA) severity and to evaluate correlations with blood levels of oxidative stress.

Study Design: Patients with OSA were diagnosed based on video-polysomnography (PSG) and blood samples were collected to evaluate oxidative stress markers: total antioxidant status (TAS), biological antioxidant potential (BAP) test, Diacron reactive oxygen metabolites (d-ROMs) test. The eyes of children with OSA were evaluated and compared with eyes of healthy age-matched children.

Pediatric hypnic headache: a systematic review.

Introduction: Hypnic headache (HH) is a primary headache, and it is considered a rare condition in children. The underlying mechanisms of HH are not yet fully understood. This systematic review aims to provide a comprehensive description of the clinical features of all published cases of pediatric HH.

Odd and Even Numbered Ferric Wheels.

The structurally related odd and even numbered wheels [Fe Zn (tea) (teaH) (OMe)Cl ] (1) and [Fe Zn (tea) Cl ] (2) can be synthesized under ambient conditions by reacting Fe and Zn salts with triethanolamine (teaH ), the change in nuclearity being dictated by the solvents employed. An antiferromagnetic exchange between nearest neighbors, J = -10.0 cm for 1 and J = -12.

A non-clinical and clinical IUCLID database for 530 pharmaceuticals (part I): Methodological aspects of its development.

A new IUCLID database is provided containing results from non-clinical animal studies and human information for 530 approved drugs. The database was developed by extracting data from pharmacological reviews of repeat-dose, carcinogenicity, developmental, and reproductive toxicity studies. In the database, observed and no-observed effects are linked to the respective effect levels, including information on severity/incidence and transiency/reversibility.

A quantum spin liquid candidate isolated in a two-dimensional CoRh bimetallic oxalate network.

A quantum spin liquid (QSL) is an elusive state of matter characterized by the absence of long-range magnetic order, even at zero temperature, and by the presence of exotic quasiparticle excitations. In spite of their relevance for quantum communication, topological quantum computation and the understanding of strongly correlated systems, like high-temperature superconductors, the unequivocal experimental identification of materials behaving as QSLs remains challenging. Here, we present a novel 2D heterometallic oxalate complex formed by high-spin Co(ii) ions alternating with diamagnetic Rh(iii) in a honeycomb lattice.

A {GdNa} Molecular Quadruple-Wheel with a Record Magnetocaloric Effect at Low Magnetic Fields and Temperatures.

Reaction of Gd(OAc)·4HO, salicylaldehyde and CHONa in MeCN/MeOH affords [GdNa(OAc)(HCO)(CO)(HO)]·9HO.0.5MeCN (·9HO.

Effects of Rapid Maxillary Expander and Delaire Mask Treatment on Airway Sagittal Dimensions in Pediatric Patients Affected by Class III Malocclusion and Obstructive Sleep Apnea Syndrome.

Obstructive sleep apnea syndrome (OSAS) is a sleep-related breathing disorder that is very common in pediatric patients. In the literature, there are very few studies concerning the association between OSAS and class III malocclusion in children. The use of a rapid maxillary expander (RME) in association with the Delaire mask is a common treatment protocol for class III malocclusion.

Towards frustration in Eu(II) Archimedean tessellations.

Self-assembly of -{EuI} nodes and ditopic ligands leads to isoreticular 2D frameworks featuring a rare, non-kagome Archimedean tessellation. The topology and intra-layer Eu(II)-Eu(II) antiferromagnetic interactions provide the prerequisites for geometrical spin frustration, which, due to the spin state degeneracy, is key for novel phenomena such as enhanced magnetic refrigeration.

Split-dose versus day-before regimen of sodium picosulfate plus magnesium citrate for bowel cleansing before colonoscopy in children: Randomized controlled trial.

Objectives: Polyethylene glycol (PEG) split-dose regimen is recommended as the option of choice for colon preparation before colonoscopy in children and adults. Sodium picosulfate plus magnesium citrate (SPMC) is equally effective but better tolerated than PEG for bowel preparation before colonoscopy in children. The aim of this study was to assess the superiority of SPMC split-dose regimen compared with SPMC day-before regimen for bowel cleansing before colonoscopy in children.

Constructing "Closed" and "Open" {Mn} Clusters.

Use of the 1,3,5-tri(2-hydroxyethyl)-1,3,5-triazacyclohexane ligand, LH, in manganese chemistry affords access to two structurally related {Mn} clusters: a "closed" {Mn Mn } puckered square wheel of formula [MnL(LH)O(OH)(MeO)Br(imH)(HO)](Br) (; imH = imidazole) and an "open" {Mn } rod of formula [Mn LO(aibH)(aib)(MeO)(MeOH)](NO) (, aibH = 2-amino-isobutyric acid). In each case the triaza ligands, L/LH, direct the formation of {Mn} triangles with their N atoms preferentially bonding to the Jahn-Teller axes of the Mn ions. Subsequent self-assembly is dependent on the anion of the Mn salt and the identity of the organic coligand employed-the terminally bonded imidazole and the chelating/bridging amino acid.

Magneto-thermal properties and slow magnetic relaxation in Mn(II)Ln(III) complexes: influence of magnetic coupling on the magneto-caloric effect.

A family of Mn(II)Ln(III) dinuclear and tetranuclear complexes (Ln = Gd and Dy) has been prepared from the compartmental ligands ,'-dimethyl-,'-bis(2-hydroxy-3-formyl-5-bromobenzyl)ethylenediamine (HL) and ,',''-trimethyl-,''-bis(2-hydroxy-3-methoxy-5-methylbenzyl)diethylenetriamine (HL). The Mn(II)Gd(III) complexes exhibit antiferromagnetic interactions between Mn(II) and Gd(III) ions in most cases, which are supported by Density Functional Theory (DFT) calculations. Experimental magneto-structural correlations carried out for the reported complexes and other related complexes found in bibliography show that the highest ferromagnetic coupling constants are observed in di-μ-phenoxido bridged complexes, which is due to the planarity of the Mn-(μ-O)-Gd bridging fragment and to the high Mn-O-Gd angles.

Psychological disorders, adverse childhood experiences and parental psychiatric disorders in children affected by headache: A systematic review.

Background: Pediatric headaches have been linked to adverse life events or psychological factors in children and their families, with a complex and bidirectional association. Moreover, it is well-known that psychological stress can trigger headaches.

Methods: We searched three databases for studies focusing on headaches and adverse events or psychological factors in children up to 12 years old or in their caregivers.

A dangerous food binge: a case report of hypokalemic periodic paralysis and review of current literature.

Background: Hypokalemic periodic paralysis is a rare neuromuscular genetic disorder due to defect of ion channels and subsequent function impairment. It belongs to a periodic paralyses group including hyperkalemic periodic paralysis (HEKPP), hypokalemic periodic paralysis (HOKPP) and Andersen-Tawil syndrome (ATS). Clinical presentations are mostly characterized by episodes of flaccid generalized weakness with transient hypo- or hyperkalemia.

Magnetism of Dendrimer-Coated Gold Nanoparticles: A Size and Functionalization Study.

Highly sensitive magnetometry reveals paramagnetism in dendrimer-coated gold nanoparticles. Different types of such nanoparticles, as a result of (i) functionalizing with two distinct Percec-type dendrons, linked to gold via dodecanethiol groups, and (ii) postsynthesis annealing in a solvent-free environment that further promotes their growth have been prepared. Ultimately, for each of the two functionalization configurations, we obtain highly monodisperse and stable nanoparticles of two different sizes, with spherical shape.

Short and Long-Term Toxicity in Pediatric Cancer Treatment: Central Nervous System Damage.

Neurotoxicity caused by traditional chemotherapy and radiotherapy is well known and widely described. New therapies, such as biologic therapy and immunotherapy, are associated with better outcomes in pediatric patients but are also associated with central and peripheral nervous system side effects. Nevertheless, central nervous system (CNS) toxicity is a significant source of morbidity in the treatment of cancer patients.

Correction: The coordination chemistry of -butylcalix[4]arene with paramagnetic transition and lanthanide metal ions: an Edinburgh Perspective.

Correction for 'The coordination chemistry of -butylcalix[4]arene with paramagnetic transition and lanthanide metal ions: an Edinburgh Perspective' by Lucinda R. B. Wilson , , 2022, DOI: 10.