Publications by authors named "Evangelina Namburete"
Article Synopsis
- The risk of stroke is highest within the first week of infective endocarditis, especially in low-resource settings where diagnostic tools are limited.
- Treatment may involve antibiotics, intravenous thrombolysis, or mechanical thrombectomy, but these carry risks of complications, particularly bleeding.
- A case is reported of a 24-year-old male with rheumatic heart disease who experienced a septic cardioembolic stroke due to infective endocarditis and received successful treatment in a low-resource environment.
Background: Mozambique is a high-burden tuberculosis (TB) country where TB/HIV co-infection and drug resistant TB (DR-TB) incidence is increasing. Whole genome sequencing (WGS) comprehensively describes the molecular epidemiology of TB, allows prediction of DR-TB phenotypes, lineages strains identification and better understanding of transmission chains.
Objective: To describe genetic diversity of DR-TB Mycobacterium tuberculosis isolated in Beira, Mozambique.
Article Synopsis
- - Mozambique has a high prevalence of tuberculosis (TB), particularly with multidrug-resistant strains and co-infection with HIV, making it a significant public health concern.
- - A study analyzed 79 suspected drug-resistant TB strains from Beira using spoligotyping and compared them to existing data, revealing four main clades of M. tuberculosis—Latin-American-Mediterranean, East-African-Indian, Beijing, and T.
- - The findings indicate that the population genetic structure of M. tuberculosis in Beira is consistent with that found throughout Mozambique, highlighting a shared genetic background of the bacteria in the region.
Tuberculosis (TB) of the testicle is a rarely reported and poorly described disease localization. There are no well-defined clinical features suggestive of testicular TB, which makes the diagnosis difficult to establish, especially in low-income settings like Mozambique, where TB is endemic and often associated with HIV-infection; both considered leading causes of death worldwide. We reported the case of a 45-year-old male, HIV positive, naïve to antiretroviral treatment, admitted to the Department of Medicine of the Central Hospital of Beira to investigate chronic enlargement of the testicles.
View Article and Find Full Text PDFAccuracy of whole genome sequencing versus phenotypic (MGIT) and commercial molecular tests for detection of drug-resistant Mycobacterium tuberculosis isolated from patients in Brazil and Mozambique.
Tuberculosis (Edinb)
May 2018
Background: The fast and accurate diagnosis of drug-resistant tuberculosis (DR-TB) is critical to reducing the spread of disease. Although commercial genotypic drug-susceptibility tests (DST) are close to the goal, they are still not able to detect all relevant DR-TB related mutations. Whole genome sequencing (WGS) allows better comprehension of DR-TB with a great discriminatory power.
View Article and Find Full Text PDFBackground: Genotypic molecular testing may be very helpful for tuberculosis (TB) drug-resistance surveillance and for treatment guidance in low resource settings.
Methods: Descriptive analysis of M. tuberculosis isolates from Beira Central Hospital, Mozambique, during 2014-2015.