Use of Hormonal Contraceptives is Associated with Decreased Incidence of ACL Injuries Requiring Reconstruction in Females.

Purpose: To investigate associations between hormonal contraceptive use and females who had sustained an ACL injury requiring reconstruction.

Methods: De-identified data were obtained from female patients 15 to 35 years of age between 2011 to 2024 from the Colorado Health Data Compass database for this study. The study was separated by females who sustained an ACL injury, treated by arthroscopic ACL reconstruction, and females without a history of ACL injury.

"An Extra Variable to Consider"-Vaccine-Induced Seropositivity and Adolescent HIV Vaccine Clinical Trials.

Our study explores the understanding of vaccine-induced seropositivity (VISP) and its potential impact on US adolescents' and caregivers' willingness to participate in adolescent HIV vaccine clinical trials. Findings from in-depth interviews suggest that addressing concerns about VISP will be essential for future pediatric HIV vaccine trials in the United States.