Restrictive pulmonary dysfunction and its predictors in young patients with β-thalassaemia major.

Background: Pulmonary dysfunction represents one of the most undervalued and less recognized complications in patients with β-thalassaemia.

Objectives: The aim of this study was to assess the pattern of pulmonary dysfunction and consequently to investigate possible associated factors that might contribute to lung impairment in young patients with β-thalassaemia major.

Methods: Fifty-two children and young adults (mean age: 21.