Correction: Suzuki coupling-based synthesis of VATPase inhibitor archazolid natural product derived fragments.

[This corrects the article DOI: 10.1039/C9RA07050H.].

Suzuki coupling-based synthesis of VATPase inhibitor archazolid natural product derived fragments.

An archazolid natural product fragment that displays dose-dependent inhibition of the vacuolar-type ATPase (VATPase) has been synthesized by a high-yielding Suzuki coupling of two complex subunits. Similarly, a further simplified fragment was prepared and evaluated for VATPase inhibitory activity. This compound did inhibit the VATPase, as evidenced by growth inhibition of etiolated seedlings, however at approximately 10× lower potency than the more complex fragment.