Publications by authors named "Evan Skwara"
Article Synopsis
- The study investigates elderly patients (over 80 years old) in Polish ICUs, aiming to understand their clinical features and outcomes.
- Researchers collected data from 371 patients, comparing frail (CFS > 4) to non-frail patients and assessing mortality rates.
- Findings indicate higher ICU and 30-day mortality in frail patients, with clinical frailty scale (CFS) and SOFA score being significant predictors of ICU mortality.
Article Synopsis
- A study was conducted to evaluate if the tendency to limit life-sustaining treatment (LST) among elderly patients in Poland increased from 2016-2017 to 2018-2019.
- The research involved analyzing data from two cohorts of critically ill patients aged over 80, finding that the prevalence of LST limitations rose from 16.1% to 20.5% over the years.
- Although the increase wasn't statistically significant in basic analyses, further investigation showed a stronger inclination to limit LST in the later cohort, along with higher mortality and longer hospital stays for patients with LST limitations.
Lafora disease (LD) and adult polyglucosan body disease (APBD) are glycogen storage diseases characterized by a pathogenic buildup of insoluble glycogen. Mechanisms causing glycogen insolubility are poorly understood. Here, in two mouse models of LD (Epm2a and Epm2b) and one of APBD (Gbe1), the separation of soluble and insoluble muscle glycogen is described, enabling separate analysis of each fraction.
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