Publications by authors named "Evan A Chrisler"
Article Synopsis
- * There's a lack of effective FDA-approved treatments for MASH despite many ongoing clinical trials, with only one drug (resmetirom) currently available, largely due to the complexity of the disease's causes.
- * To improve treatment through precision medicine, it's essential to understand how genetics, diet, and gut microbiome interplay, and further research is needed to address existing knowledge gaps.
Circadian rhythms govern glucose homeostasis, and their dysregulation leads to complex metabolic diseases. Gut microbes exhibit diurnal rhythms that influence host circadian networks and metabolic processes, yet underlying mechanisms remain elusive. Here, we showed hierarchical, bidirectional communication among the liver circadian clock, gut microbes, and glucose homeostasis in mice.
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