Publications by authors named "Eva-Maria Konrad"
Background And Purpose: This study explores the use of deep learning (DL) techniques in MRI of the orbit to enhance imaging. Standard protocols, although detailed, have lengthy acquisition times. We investigate DL-based methods for T2-weighted and T1-weighted, fat-saturated, contrast-enhanced turbo spin echo (TSE) sequences, aiming to improve image quality, reduce acquisition time, minimize artifacts, and enhance diagnostic confidence in orbital imaging.
View Article and Find Full Text PDFAim: To evaluate the impact of the optical coherence tomography (OCT) scan patterns on the detection of the features associated with lamellar macular hole (LMH) and macular pseudohole (MPH).
Methods: This is a retrospective analysis of 100 consecutive eyes with LMH (=41) and MPH (=59) having at least three of the following OCT features, which include mandatory criteria for the diagnosis of LMH and MPH: Epiretinal membrane, epiretinal proliferation, verticalization, intraretinal cystoid spaces, foveoschisis, irregular foveal contour, foveal cavity with undermined edges, and ellipsoid line disruption. Primary outcome measurement was the detection frequency of the features in three different OCT scan patterns: 1) volume scan; 2) six radial scans (R6); and 3) vertical and horizontal radial scans (R2).
Article Synopsis
- - This study investigated how the success of corneal crosslinking (CXL) for treating progressive keratoconus varies depending on the stage of the disease when the treatment is performed.
- - Data from 124 eyes of 100 patients were analyzed, focusing on visual acuity, astigmatism, and corneal measurements before and after the procedure over a period from November 2008 to September 2018.
- - Results indicated that patients with earlier stages of keratoconus showed significantly better improvements in visual acuity after CXL compared to those with more advanced stages, suggesting that early treatment may lead to better outcomes.
Successful Regression in Patients with Progressive Keratoconus by Corneal Crosslinking.
Klin Monbl Augenheilkd
November 2021
Background: Since 2019, corneal collagen crosslinking (CXL) is included in the catalog of procedures covered by statutory health insurance in Germany. CXL is an established ophthalmological procedure for the last 20 years. The aim of this investigation was the measurement of progression before and after CXL.
View Article and Find Full Text PDFPurpose: Glaucoma filtration surgery (GFS) fails due to fibrosis. The α5β1-integrin plays a pivotal role in fibrosis, angiogenesis and inflammation. This is the first experiment evaluating the prevention of fibrosis after GFS by a specific small molecule α5β1-integrin inhibitor (CLT-28643).
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