Fatigue in a simple repetitive motor task: a combined electrophysiological and neuropsychological study.

Fatigue is one of the most common psychophysiological symptoms that interact with the control mechanisms regulating task behaviour. The cortical processes involved in preparation and feedback control of voluntary movement are associated with EEG activity time-locked to movement onset: a pre-movement Movement-Related Cortical Potential (MRCP) is followed by a post-movement potential (PMP). The aim of this study was to determine whether changes in subjective fatigue which arise in the course of a simple repetitive motor task affect cortical information processing as measured by MRCPs or PMPs.