Altered frontal and temporal brain function during olfactory stimulation in adult attention-deficit/hyperactivity disorder.

Objective: Olfactory processing depends on dopamine metabolism and orbitofrontal cortex functioning, both known to be disturbed in attention-deficit/hyperactivity disorder (ADHD). Some investigations suggested alterations in olfactory processing (identification and sensitivity) in childhood and adult ADHD.

Methods: In the present study we investigated olfactory function (Sniffin' Sticks) of 29 adult patients with ADHD (17 combined, 11 inattentive, and 1 hyperactive/impulsive subtype) and 29 controls matched for sex, handedness, age, intelligence, and education.

Tardive dyskinesia and new antipsychotics.

Purpose Of Review: To provide an update on tardive dyskinesia rates in patients treated with first-generation or second-generation antipsychotics in studies published since the last systematic review in 2004.

Recent Findings: Across 12 trials (n = 28 051, age 39.7 years, 59.