Effect of neuromuscular blockade on the bispectral index in critically ill patients.

Introduction: It has been suggested that neuromuscular blockade (NMB) affects the capacity of bispectral index (BIS) monitoring to measure consciousness in sedated children. Our aim was to analyse the impact of NMB on BIS values in critically ill children.

Methods: We conducted a prospective observational study of children monitored with a BIS system that received a continuous infusion of vecuronium.

[Effect of neuromuscular blockade on the bispectral index in critically ill patients].

Introduction: It has been suggested that neuromuscular blockade (NMB) affects the capacity of bispectral index (BIS) monitoring to measure consciousness in sedated children. Our aim was to analyse the impact of NMB on BIS values in critically ill children.

Methods: We conducted a prospective observational study of children monitored with a BIS system that received a continuous infusion of vecuronium.

Sedative and Analgesic Drug Rotation Protocol in Critically Ill Children With Prolonged Sedation: Evaluation of Implementation and Efficacy to Reduce Withdrawal Syndrome.

Objectives: The first aim of this study was to assess the implementation of a sedative and analgesic drug rotation protocol in a PICU. The second aim was to analyze the incidence of withdrawal syndrome, drug doses, and time of sedative or analgesic drug infusion in children after the implementation of the new protocol.

Design: Prospective observational study.