Crystal structures and Hirshfeld surface analyses of bis-(4,5-di-hydro-furan-2-yl)di-methyl-silane and (4,5-di-hydro-furan-2-yl)(meth-yl)di-phenyl-silane.

The title compounds, CHOSi () and CHOSi (), are classified as di-hydro-furylsilanes, which show great potential as building blocks for various functionalized silanes. They both crystallize in the space group in the triclinic crystal system. Analyses of the Hirshfeld surfaces show packing-determining inter-actions for both compounds, resulting in a polymeric chain along the [011] for silane and a layered-inter-connected structure along the -axis direction for silane .

Crystal structures, Hirshfeld atom refinements and Hirshfeld surface analyses of tris-(4,5-di-hydro-furan-2-yl)methyl-silane and tris-(4,5-di-hydro-furan-2-yl)phenyl-silane.

The title compounds, CHOSi () and CHOSi (), represent functional-izable di-hydro-furan-ylsilanes, which permit substitution by a variety of nucleophiles. The crystal structures of and display weak inter-molecular C-H⋯O hydrogen-bonding inter-actions (qu-anti-fied by Hirshfeld surface analysis), leading to a two-dimensional supra-molecular network for and a one-dimensional supra-molecular network for . The crystal structures of and were refined both on the basis of the independent atom model (IAM) and the Hirshfeld atom refinement (HAR) approach, and the results are comparatively discussed.

Crystal structure of di-μ-iodido-bis{[bis(piperidin-1-yl)methane-κ(2) N,N']copper(I)}.

The title compound, [Cu2I2(C11H22N2)2], crystallizes as a symmetric dimer with one quarter of the mol-ecule in the asymmetric unit. The copper(I) atom, the iodine atom and the central methyl-ene C atom of the di(piperidin-1-yl)methane ligand lie on a mirror plane and the complete molecule exhibits point group symmetry 2/m. To the best of our knowledge it is the first di-amine copper(I) complex containing a four-membered chelate ring.

Crystal structure of di-μ-iodido-bis-[bis(aceto-nitrile-κN)copper(I)].

The title compound, [Cu2I2(CH3CN)4], exhibits a centrosymmetric Cu2I2 core [Cu⋯Cu distance = 2.7482 (11) Å], the Cu(I) atoms of which are further coordinated by four mol-ecules of aceto-nitrile. The Cu(I) atom has an overall distorted tetra-hedral coordination environment evidenced by L-Cu-L angles (L = N or I) ranging from 100.

Crystal structure of benz-yl(meth-yl)phen-yl[(piperidin-1-ium-1-yl)meth-yl]silane bromide.

The title compound, C20H29NSi(+)·Br(-), contains a chiral silicon atom but crystallizes as a racemate. The C-Si-C bond angles in the range of 103.64 (8)-111.

Conjugation of Ciprofloxacin with Poly(2-oxazoline)s and Polyethylene Glycol via End Groups.

The antibiotic ciprofloxacin (CIP) was covalently attached to the chain end of poly(2-methyloxazoline) (PMOx), poly(2-ethyloxazoline) (PEtOx), and polyethylene glycol (PEG), and the antimicrobial activity of these conjugates was tested for Staphylococcus aureus, Streptococcus mutans, Escherichia coli, Pseudomonas aeruginosa, and Kleisella pneumoniae. Chemical structures of the conjugates were proven by (1)H NMR and electron spray ionization mass spectrometry. The direct coupling of PMOx and CIP resulted in low antimicrobial activity.